A series of novel and selective N-[3-(6-benzyloxy-3-methoxyphenyl) propyl] amides has
recently been shown to possess sub-nanomolar range binding affinity to the type 2 …

A series of substituted N-[3-(3-methoxyphenyl) propyl] amides were synthesized and their
binding affinities towards human melatonin MT1 and MT2 receptors were evaluated. It was …

A series of N-(2-phenylbenzofuran-3-yl) ethyl amide and N-(2-arylalkylbenzofuran-3-yl) ethyl
amide derivatives were synthesized and evaluated as melatonin receptor ligands. The …

This work reports the design and synthesis of novel alkylamides, characterized by a dibenzo
[a, d] cycloheptene nucleus, as melatonin (MLT) receptor ligands. The tricyclic scaffold was …

The design of compounds selective for the MT1 melatonin receptor is still a challenging task
owing to the limited knowledge of the structural features conferring selectivity for the MT1 …

A series of naphthalenic analogues of melatonin were prepared and evaluated as melatonin
receptor MT2 selective ligands. Activity and MT2 selectivity can be modulated with suitable …

N-{2-[2-(4-Phenylbutyl)benzofuran-4-yl]cyclopropylmethyl}acetamide: an orally bioavailable
melatonin receptor agonist - ScienceDirect Skip to main contentSkip to article Elsevier logo …

We report the synthesis, binding properties and intrinsic activity at MT1 and MT2 melatonin
receptors of new dimeric melatonin receptor ligands in which two units of the monomeric …

Two series of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide
derivatives exhibiting diverse functionality at rat MT1 and MT2 receptors are reported …

Melatonin is a widely distributed hormone that regulates several major physiological
processes, including the circadian rhythm and seasonal adaptation. The two subtypes of …