[HTML][HTML] Mid-regional pro-adrenomedullin (MR-proADM) as a biomarker for sepsis and septic shock: narrative review

U Önal, F Valenzuela-Sánchez, KE Vandana, J Rello - Healthcare, 2018 - mdpi.com
Early identification and diagnosis of sepsis and septic shock is vitally important; despite
appropriate management, mortality and morbidity rates remain high. For this reason, many …

[HTML][HTML] Proadrenomedullin in sepsis and septic shock: a role in the emergency department

A Piccioni, A Saviano, S Cicchinelli, F Valletta… - Medicina, 2021 - mdpi.com
Sepsis and septic shock represent a leading cause of mortality in the Emergency
Department (ED) and in the Intensive Care Unit (ICU). For these life-threating conditions …

[HTML][HTML] New role of biomarkers: mid-regional pro-adrenomedullin, the biomarker of organ failure

F Valenzuela-Sánchez… - Annals of …, 2016 - ncbi.nlm.nih.gov
Mid-regional pro-adrenomedullin (MR-proADM) has a good biomarker profile: its half-life is
several hours, and its plasma concentrations can be determined in clinical practice, it is …

Usefulness of midregional pro-adrenomedullin as a marker of organ damage and predictor of mortality in patients with sepsis

E Bernal-Morell, E García-Villalba, M del Carmen Vera… - Journal of Infection, 2018 - Elsevier
Abstract Background Midregional proadrenomedullin (MR-proADM) is a prognostic
biomarker in patients with community-acquired pneumonia (CAP) and sepsis. In this paper …

[HTML][HTML] Mid-Regional Pro-Adrenomedullin Can Predict Organ Failure and Prognosis in Sepsis?

S Spoto, S Basili, R Cangemi, G D'Avanzo… - International Journal of …, 2023 - mdpi.com
Sepsis causes immune dysregulation and endotheliitis, with an increase in mid-regional pro-
adrenomedullin (MR-proADM). The aim of the study is to determine an MR-proADM value …

Prognostic value of proadrenomedullin in severe sepsis and septic shock patients with community-acquired pneumonia

B Suberviola, A Castellanos-Ortega, J Llorca… - Swiss Medical …, 2012 - smw.ch
PRINCIPLES: Midregional proadrenomedullin (proADM) is a novel biomarker with potential
prognostic utility in patients with community-acquired pneumonia. The aim of this study was …

[HTML][HTML] The use of mid-regional proadrenomedullin to identify disease severity and treatment response to sepsis-a secondary analysis of a large randomised …

G Elke, F Bloos, DC Wilson, FM Brunkhorst, J Briegel… - Critical Care, 2018 - Springer
Background This study assessed the ability of mid-regional proadrenomedullin (MR-
proADM) in comparison to conventional biomarkers (procalcitonin (PCT), lactate, C-reactive …

[HTML][HTML] Superior accuracy of mid-regional proadrenomedullin for mortality prediction in sepsis with varying levels of illness severity

D Andaluz-Ojeda, HB Nguyen, N Meunier-Beillard… - Annals of intensive …, 2017 - Springer
Background The use of novel sepsis biomarkers has increased in recent years. However,
their prognostic value with respect to illness severity has not been explored. In this work, we …

Mid-regional pro-adrenomedullin predicts poor outcome in non-selected patients admitted to an intensive care unit

C Bellia, L Agnello, B Lo Sasso, G Bivona… - Clinical Chemistry and …, 2019 - degruyter.com
Background Mortality risk and outcome in critically ill patients can be predicted by scoring
systems, such as APACHE and SAPS. The identification of prognostic biomarkers, simple to …

[HTML][HTML] Mid-regional proadrenomedullin: An early marker of response in critically ill patients with severe community-acquired pneumonia?

JM Pereira, A Azevedo, C Basilio, C Sousa-Dias… - Revista Portuguesa de …, 2016 - Elsevier
Background Mid-regional proadrenomedullin (MR-proADM) is a novel biomarker with
potential prognostic utility in patients with community-acquired pneumonia (CAP). Purpose …