Gut microbiota consists of over 100 trillion microorganisms including at least 1000 different
species of bacteria and is crucially involved in physiological and pathophysiological …

Alzheimer's disease (AD) is a progressive, age-related neurodegenerative disorder that
affects a large proportion of the older population. It currently lacks effective treatments …

Structural and functional alterations to the gut microbiome, referred to as gut dysbiosis, have
emerged as potential key mediators of neurodegeneration and Alzheimer disease (AD) …

Alzheimer's disease (AD) is the most common cause of dementia. Epidemiological studies
show the association between AD and type 2 diabetes (T2DM), although the mechanisms …

Increasing evidence gives support for the idea that extra-neuronal factors may affect brain
physiology and its predisposition to neurodegenerative diseases. Epidemiological and …

Alzheimer's disease (AD) is a complex, multi-factorial disease affecting various brain
systems. This complexity implies that successful therapies must be directed against several …

Background: Mild cognitive impairment (MCI) and Alzheimer's disease (AD) are common in
older adults. Much recent work has implicated the connection between the gut and the brain …

The number of bacterial cells living within the human body is approximately equal to, or
greater than, the total number of human cells. This dynamic population of microorganisms …

Interest in the gut–brain axis and its implications for neurodegenerative diseases, such as
Alzheimer's disease and related dementias, is growing. Microbial imbalances in the …

A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …