Hyperuricemia and gout are complex diseases mediated by genetic, epigenetic, and
environmental exposure interactions. The incidence and medical burden of gout, an …

Gout is the most common form of inflammatory arthritis in adults. Elevation serum uric acid
(SUA) concentration is known to be the key to gout pathogenesis. Since the first genome …

Gout is an inflammatory condition caused by elevated serum urate (SU), a condition known
as hyperuricemia (HU). Genetic variations, including single nucleotide polymorphisms …

The pathogenesis of gout involves a series of steps beginning with hyperuricaemia, followed
by the deposition of monosodium urate crystal in articular structures and culminating in an …

This review focuses on the post-genome-wide association study (GWAS) era in gout, ie, the
translation of GWAS genetic association signals into biologically informative knowledge …

Gout is a common type of inflammatory arthritis that is clinically and genetically
heterogeneous. The genetic aetiology remains unclear, and mainly relies on previous …

Background/Purpose: Genome-wide association studies (GWAS) in gout have been
relatively small (≤ 13,179 people with gout) and have provided little insight into the …

Gout is the most frequent form of inflammatory arthritis in the world. Its prevalence is
particularly elevated in specific geographical areas such as in the Oceania/Pacific region …

Gout is a chronic metabolic disease that seriously affects human health. It is also a major
challenge facing the world, which has brought a heavy burden to patients and society …

Gout is a chronic disease of monosodium urate crystal deposition in the setting of
hyperuricemia that typically presents with recurrent flares of acute inflammatory arthritis that …