Pseudomonas aeruginosa is capable of natural transformation in biofilms

LM Nolan, L Turnbull, M Katrib, SR Osvath… - …, 2020 - microbiologyresearch.org
Natural transformation is a mechanism that enables competent bacteria to acquire naked,
exogenous DNA from the environment. It is a key process that facilitates the dissemination of …

[HTML][HTML] Genetic determinants of Pseudomonas aeruginosa fitness during biofilm growth

S Schinner, F Engelhardt, M Preusse, JG Thöming… - Biofilm, 2020 - Elsevier
Pseudomonas aeruginosa is an environmental bacterium and an opportunistic human
pathogen. It is also a well-established model organism to study bacterial adaptation to …

A genetic switch controls Pseudomonas aeruginosa surface colonization

C Manner, R Dias Teixeira, D Saha… - Nature …, 2023 - nature.com
Efficient colonization of mucosal surfaces is essential for opportunistic pathogens like
Pseudomonas aeruginosa, but how bacteria collectively and individually adapt to optimize …

Strain-specific parallel evolution drives short-term diversification during Pseudomonas aeruginosa biofilm formation

KE McElroy, JGK Hui, JKK Woo… - Proceedings of the …, 2014 - National Acad Sciences
Generation of genetic diversity is a prerequisite for bacterial evolution and adaptation. Short-
term diversification and selection within populations is, however, largely uncharacterised, as …

SadB Is Required for the Transition from Reversible to Irreversible Attachment during Biofilm Formation by Pseudomonas aeruginosa PA14

NC Caiazza, GA O'Toole - 2004 - Am Soc Microbiol
Current models of biofilm formation by Pseudomonas aeruginosa propose that (i) planktonic
cells become surface associated in a monolayer,(ii) surface-associated cells form …

Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment

MH Rau, RL Marvig, GD Ehrlich… - Environmental …, 2012 - Wiley Online Library
Adaptation of bacterial pathogens to a permanently host‐associated lifestyle by means of
deletion or acquisition of genetic material is usually examined through comparison of …

A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms

M Allesen‐Holm, KB Barken, L Yang… - Molecular …, 2006 - Wiley Online Library
Pseudomonas aeruginosa produces extracellular DNA which functions as a cell‐to‐cell
interconnecting matrix component in biofilms. Comparison of extracellular DNA and …

Interstrain transfer of the large pathogenicity island (PAPI-1) of Pseudomonas aeruginosa

X Qiu, AU Gurkar, S Lory - Proceedings of the National …, 2006 - National Acad Sciences
The large Pseudomonas aeruginosa pathogenicity island PAPI-1 of strain PA14 is a cluster
of 108 genes that encode a number of virulence features. We demonstrate that, in a …

A rapid seamless method for gene knockout in Pseudomonas aeruginosa

W Huang, A Wilks - BMC microbiology, 2017 - Springer
Background Pseudomonas aeruginosa is a model organism for the study of quorum
sensing, biofilm formation, and also leading cause of nosocomial infections in immune …

Temperate phages both mediate and drive adaptive evolution in pathogen biofilms

EV Davies, CE James, D Williams… - Proceedings of the …, 2016 - National Acad Sciences
Temperate phages drive genomic diversification in bacterial pathogens. Phage-derived
sequences are more common in pathogenic than nonpathogenic taxa and are associated …