Chronic lung infections with Pseudomonas aeruginosa biofilms are associated with
refractory and fatal pneumonia in cystic fibrosis (CF). In this study, a group of genomically …

Pseudomonas aeruginosa is a ubiquitous environmental bacterium capable of forming
biofilms on surfaces as a survival strategy. It exhibits a large variety of competition/virulence …

Mature Pseudomonas aeruginosa biofilms form complex three-dimensional architecture and
are tolerant of antibiotics and other antimicrobial compounds. In this work, an in vivo …

Bacterial cooperative associations and dynamics in biofilm microenvironments are of special
interest in recent years. Knowledge of localized gene‐expression and corresponding …

The first Pseudomonas genome was sequenced in 2000, and at 6.3 million base pairs, it
was, at the time, the largest bacterial genome ever sequenced (Stover et al., 2000). Not …

Horizontal gene flow is a driving force for bacterial adaptation. Among the three distinct
mechanisms of gene transfer in bacteria, conjugation, transduction, and transformation, the …

To achieve systemic infection, bacterial pathogens must overcome the critical and
challenging step of transmigration across epithelial barriers. This is particularly true for …

Pseudomonas aeruginosa is a gram-negative opportunistic pathogen often associated with
nosocomial infections that are made more severe by this bacterium's ability to form robust …

Mature Pseudomonas aeruginosa biofilms undergo specific developmental events. Using a
bacteriophage mutant, generated by deletion of the entire filamentous Pf4 prophage, we …

Pseudomonas aeruginosa is a versatile opportunistic pathogen causing a wide variety of
hospital-acquired acute infections in immunocompromised patients as well as chronic …