Infection of mucosal tissues by the opportunistic pathogen Pseudomonas aeruginosa is
initiated by attachment of the bacterium to host tissues. To gain a better understanding of this …

Biofilm growth increases the fitness of bacteria in harsh conditions. However, bacteria from
clinical and environmental biofilms can exhibit impaired growth in culture, even when the …

Natural genetic transformation is widely distributed in bacteria and generally occurs during a
genetically programmed differentiated state called competence. This process promotes …

Highlights•Natural transformation mediates the spread of antibiotic resistance
genes.•Natural transformation can aid gene transfer between unrelated taxa.•Natural …

Chronic biofilm infections by Pseudomonas aeruginosa are a major contributor to the
morbidity and mortality of patients. The formation of multicellular bacterial aggregates, called …

The complete DNA sequence of Pseudomonas aeruginosa provides an opportunity to apply
functional genomics to a major human pathogen. A comparative genomics approach …

Pseudomonas aeruginosa biofilm-related infections are difficult to treat with antibiotics.
Along the different layers of the biofilm, the P. aeruginosa population is heterogeneous …

Pseudomonas aeruginosa is a common, free‐living, Gram‐negative bacterium that can
cause significant disease as an opportunistic pathogen. Rapid growth, facile genetics, and a …

Bacteria growing in biofilms often develop multicellular, three-dimensional structures known
as microcolonies. Complex differentiation within biofilms of Pseudomonas aeruginosa …

Pseudomonas aeruginosa is an important opportunistic pathogen causing chronic airway
infections, especially in cystic fibrosis (CF) patients. The majority of the CF patients acquire …