Aging biomarkers: from functional tests to multi‐omics approaches

KS Kudryashova, K Burka, AY Kulaga… - …, 2020 - Wiley Online Library
Aging results in various deleterious changes in the human body that may lead to loss of
function and the manifestation of chronic diseases. While diseases can generally be reliably …

Promising biomarkers of human aging: In search of a multi-omics panel to understand the aging process from a multidimensional perspective

NA Rivero-Segura, OY Bello-Chavolla… - Ageing research …, 2020 - Elsevier
The aging process has been linked to the occurrence of chronic diseases and functional
impairments, including cancer, sarcopenia, frailty, metabolic, cardiovascular, and …

Biomarkers of aging

Aging Biomarker Consortium, H Bao, J Cao… - Science China Life …, 2023 - Springer
Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Integration of 'omics' data in aging research: from biomarkers to systems biology

J Zierer, C Menni, G Kastenmüller, TD Spector - Aging cell, 2015 - Wiley Online Library
Age is the strongest risk factor for many diseases including neurodegenerative disorders,
coronary heart disease, type 2 diabetes and cancer. Due to increasing life expectancy and …

[HTML][HTML] Molecular and phenotypic biomarkers of aging

X Xia, W Chen, J McDermott, JDJ Han - F1000Research, 2017 - ncbi.nlm.nih.gov
Individuals of the same age may not age at the same rate. Quantitative biomarkers of aging
are valuable tools to measure physiological age, assess the extent of 'healthy aging', and …

Emerging omics approaches in aging research

JS Lorusso, OA Sviderskiy… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Aging is a complex trait that is influenced by a combination of genetic and
environmental factors. Although many cellular and physiological changes have been …

Multi-omics approaches to human biological age estimation

I Solovev, M Shaposhnikov, A Moskalev - Mechanisms of Ageing and …, 2020 - Elsevier
Multi-omics approach nowadays increasingly applied to molecular research in many fields
of life sciences. Biogerontology is not an exception; multi-omics gives possibility to evaluate …

Biomarkers of aging: from function to molecular biology

KH Wagner, D Cameron-Smith, B Wessner, B Franzke - Nutrients, 2016 - mdpi.com
Aging is a major risk factor for most chronic diseases and functional impairments. Within a
homogeneous age sample there is a considerable variation in the extent of disease and …

Integrated multi-omics for novel aging biomarkers and antiaging targets

L Wu, X Xie, T Liang, J Ma, L Yang, J Yang, L Li, Y Xi… - Biomolecules, 2021 - mdpi.com
Aging is closely related to the occurrence of human diseases; however, its exact biological
mechanism is unclear. Advancements in high-throughput technology provide new …

[HTML][HTML] Biomarkers of aging in frailty and age-associated disorders: State of the art and future perspective

S Salvioli, MS Basile, L Bencivenga, S Carrino… - Ageing Research …, 2023 - Elsevier
According to the Geroscience concept that organismal aging and age-associated diseases
share the same basic molecular mechanisms, the identification of biomarkers of age that can …