Fluid‐structure interaction analysis of a collapsible axial flow blood pump impeller and protective cage for Fontan patients

M Hirschhorn, E Bisirri, R Stevens… - Artificial …, 2020 - Wiley Online Library
Limited donor organs and alternative therapies have led to a growing interest in the use of
blood pumps as a treatment strategy for patients with single functional ventricle. The present …

Design of Axial Blood Pumps for Patients With Dysfunctional F ontan Physiology: Computational Studies and Performance Testing

DH Kafagy, TW Dwyer, KL McKenna, JP Mulles… - Artificial …, 2015 - Wiley Online Library
Limited treatment options for patients having dysfunctional single ventricle physiology
motivate the necessity for alternative therapeutic options. To address this unmet need, we …

Design of a protective cage for an intravascular axial flow blood pump to mechanically assist the failing Fontan

AL Throckmorton, RA Kishore - Artificial organs, 2009 - Wiley Online Library
Currently, no long‐term mechanical bridge‐to‐transplant or bridge‐to‐recovery therapeutic
alternative exists for failing single ventricles. A blood pump that would augment pressure in …

Numerical, hydraulic, and hemolytic evaluation of an intravascular axial flow blood pump to mechanically support Fontan patients

AL Throckmorton, JY Kapadia, SG Chopski… - Annals of biomedical …, 2011 - Springer
Currently available mechanical circulatory support systems are limited for adolescent and
adult patients with a Fontan physiology. To address this growing need, we are developing a …

Flexible impeller blades in an axial flow pump for intravascular cavopulmonary assistance of the Fontan physiology

AL Throckmorton, JY Kapadia, JP Carr… - Cardiovascular …, 2010 - Springer
An intravascular axial flow blood pump has suitable hydraulic characteristics for use to
augment pressure in the cavopulmonary circulation in Fontan patients. This study presents …

Twisted cardiovascular cages for intravascular axial flow blood pumps to support the Fontan physiology

AL Throckmorton, EA Downs… - … Journal of Artificial …, 2012 - journals.sagepub.com
Failing single ventricle physiology represents an ongoing challenge in mechanical assist
device development, requiring pressure augmentation in the cavopulmonary circuit …

Mechanical cavopulmonary assistance of a patient‐specific Fontan physiology: numerical simulations, lumped parameter modeling, and suction experiments

AL Throckmorton, JP Carr, SA Tahir, R Tate… - Artificial …, 2011 - Wiley Online Library
This study investigated the performance of a magnetically levitated, intravascular axial flow
blood pump for mechanical circulatory support of the thousands of Fontan patients in …

Pressure–flow experimental performance of new intravascular blood pump designs for Fontan patients

SG Chopski, CS Fox, ML Riddle, KL McKenna… - Artificial …, 2016 - Wiley Online Library
An intravascular axial flow pump is being developed as a mechanical cavopulmonary assist
device for adolescent and adult patients with dysfunctional F ontan physiology. Coupling …

Hydraulic testing of intravascular axial flow blood pump designs with a protective cage of filaments for mechanical cavopulmonary assist

JY Kapadia, KC Pierce, AK Poupore… - ASAIO …, 2010 - journals.lww.com
To provide hemodynamic support to patients with a failing single ventricle, we are
developing a percutaneously inserted, magnetically levitated axial flow blood pump …

Filament support spindle for an intravascular cavopulmonary assist device

AL Throckmorton, JY Kapadia… - Artificial …, 2010 - Wiley Online Library
We are developing an intravascular axial flow blood pump to support adolescent and adult
Fontan patients. To protect the blood vessel, this pump has an outer cage with radially …