[HTML][HTML] A novel mismatched PCR-restriction fragment length polymorphism assay for rapid detection of gyrA and parC mutations associated with fluoroquinolone …

N Kakuta, R Nakano, A Nakano, Y Suzuki… - Annals of Laboratory …, 2020 - ncbi.nlm.nih.gov
Background Mutations in the quinolone resistance-determining regions (QRDRs) of
Acinetobacter baumannii DNA gyrase (gyrA) and topoisomerase IV (parC) are linked to …

Mutations in gyrA and parC genes in fluoroquinolone-resistant Acinetobacter baumannii that causes hospital acquired infection

MS Taha, SM Shoeib… - Microbes and Infectious …, 2023 - journals.ekb.eg
Background: Acinetobacter baumannii, are involved in hospital-acquired infections and are
increasingly developing resistance to fluoroquinolones, such as ciprofloxacin. The most …

Impact of target site mutations and plasmid associated resistance genes acquisition on resistance of Acinetobacter baumannii to fluoroquinolones

MA Mohammed, MTA Salim, BE Anwer… - Scientific Reports, 2021 - nature.com
Among bacterial species implicated in hospital-acquired infections are the emerging Pan-
Drug Resistant (PDR) and Extensively Drug-Resistant (XDR) Acinetobacter (A.) baumannii …

[PDF][PDF] PCR-RFLP-Based detection of mutations in the chromosomal fluoroquinolone targets gyrA and parC genes of Acinetobacter baumanii clinical isolates from a …

MM Tawfick, MI El-Borhamy - Am J of Microb …, 2017 - article.microbiologicalresearch.com
Abstract Background and Aim: Acinetobacter baumannii is one of the most antimicrobial
resistant nosocomial pathogens encountered clinically worldwide. The emergence of …

Mutations in gyrA and parC associated with resistance to fluoroquinolones in epidemiologically defined clinical strains of Acinetobacter baumannii

H Wisplinghoff, M Decker, C Haefs… - Journal of …, 2003 - academic.oup.com
Sir, Acinetobacter baumannii has emerged as a significant nosocomial pathogen. Major
epidemiological features of these organisms are their multidrug resistance, propensity for …

Frequency of chromosomally encoded gyrA and parC genetic determinants of fluoroquinolone resistance in A. Baumannii

AK Singh, AS Girija, JV Priyadharsini, A Paramasivam - 2020 - pesquisa.bvsalud.org
Fluoroquinolones are administered as routine drugs of choice for treating complicated
urinary tract infections caused by multidrug resistant Acinetobacter baumannii strains. It is …

[HTML][HTML] Association between mutations in gyrA and parC genes of Acinetobacter baumannii clinical isolates and ciprofloxacin resistance

A Ardebili, AR Lari, M Beheshti… - Iranian journal of basic …, 2015 - ncbi.nlm.nih.gov
Objective (s): We investigated the contribution of gyrA and parC mutational mechanism in
decreased ciprofloxacin susceptibility of Acinetobacter baumannii isolated from burn wound …

[HTML][HTML] Molecular study of quinolone resistance determining regions of gyrA gene and parC genes in clinical isolates of Acintobacter baumannii resistant to …

MES Zaki, N Abou ElKheir, M Mofreh - The Open Microbiology …, 2018 - ncbi.nlm.nih.gov
Materials and Methods: The study was carried out on 140 clinical isolates of A. baumannii.
The isolates were subjected to molecular study of mutations of gyrA gene and parC genes …

A fluoroquinolone-resistant Acinetobacter baumannii without the quinolone resistance-determining region mutations

S Chopra, A Galande - Journal of antimicrobial chemotherapy, 2011 - academic.oup.com
Sir, Acinetobacter baumannii is an emerging Gram-negative multidrug-resistant (MDR)
nosocomial pathogen responsible for causing lung, bloodstream, urinary tract and skin …

[PDF][PDF] Mutations in the quinolone resistance determining region in isogenic mutant Acinetobacter baumannii strains

L Hongbo, S Zhen, X Xiaoman… - Afr. J. Microbiol …, 2013 - academicjournals.org
The aim of the study is to explore the change or mutation of DNA gyrase (gyrA) and
topoisomerase IV (parC) in Quinolone Resistance Determining Region (QRDR) in …