Effect of regulatory T cells and adherent cells on the expansion of HBcAg-specific CD8+ T cells in patients with chronic hepatitis B virus infection

X Li, Y Chen, Z Ma, B Ye, W Wu, L Li - Cellular immunology, 2010 - Elsevier
Patients with chronic HBV infection show poor immune response to HBV-specific CD8+ T
cells. Several studies demonstrate that regulatory T cells (Treg) and dendritic cells (DC) are …

Inhibition of CD4+ CD25+ regulatory T cells in chronic hepatitis B patients

HH Zhang, F Guo, R Fei, H Ma, X Cong, L Wei… - Zhonghua yi xue za …, 2008 - europepmc.org
To evaluate the inhibition of CD4+ CD25+ regulatory T cells (Treg) in the chronic hepatitis B
patients. Peripheral blood samples were collected from 22 patients with chronic hepatitis B …

Circulating CD4+CD25high Regulatory T Cells and Expression of PD-1 and BTLA on CD4+ T Cells in Patients with Chronic Hepatitis B Virus Infection

XP Nan, Y Zhang, HT Yu, Y Li, RL Sun, JP Wang… - Viral …, 2010 - liebertpub.com
The roles of regulatory T cells (Tregs) and PD-1 in hepatitis B have not been clearly
described. Also, the role of B and T lymphocyte attenuator (BTLA), which serves as a …

Circulating CD4+ CD25+ regulatory T cells correlate with chronic hepatitis B infection

G Peng, S Li, W Wu, Z Sun, Y Chen, Z Chen - Immunology, 2008 - Wiley Online Library
Summary Circulating CD4+ CD25+ regulatory T cells (Tregs) have been demonstrated to
maintain immunotolerance and suppress the antigen‐specific or antigen‐non‐specific T‐cell …

Circulating regulatory Tfh cells are enriched in patients with chronic hepatitis B infection and induce the differentiation of regulatory B cells

R Wang, R Xie, Z Song - Experimental Cell Research, 2018 - Elsevier
Chronic hepatitis B virus (HBV) infection is a complex disease with dysregulations in the
immune system. Follicular helper T (Tfh) cells are professional B helper cells that are crucial …

Circulating and liver resident CD4+ CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B

D Xu, J Fu, L Jin, H Zhang, C Zhou, Z Zou… - The Journal of …, 2006 - journals.aai.org
Abstract CD4+ CD25+ regulatory T cells (Treg) have been shown to maintain immune
tolerance against self and foreign Ags, but their role in persistent viral infection has not been …

The characterization of regulatory T cells in peripheral blood of HBV-infected patients

JL Fu, DP Xu, P Zhao, LM Chen, H Zhang… - Zhonghua yi xue za …, 2006 - europepmc.org
Objective CD4 (+) CD25 (high) regulatory T cells (Treg) have been shown to play an
important role in maintaining peripheral tolerance against self and foreign antigens, and in …

Modulation of the CD8+-T-Cell Response by CD4+ CD25+ Regulatory T Cells in Patients with Hepatitis B Virus Infection

O Franzese, PTF Kennedy, AJ Gehring, J Gotto… - Journal of …, 2005 - Am Soc Microbiol
ABSTRACT CD4+ CD25+ regulatory T cells have been shown to maintain peripheral
tolerance against self and foreign antigens. In this study we analyzed the effect of circulating …

Kinetics of peripheral hepatitis B virus-specific CD8+ T cells in patients with onset of viral reactivation

J Aoki, Y Kowazaki, T Ohtsuki, R Okamoto… - Journal of …, 2013 - Springer
Background Patients with resolved hepatitis B virus (HBV) infection undergoing
chemotherapy or immunosuppressive therapy are potentially at risk of HBV reactivation …

Human plasmacytoid dendritic cells from patients with chronic hepatitis B virus infection induce the generation of a higher proportion of CD4+ and CD25+ regulatory …

J Hong, ZJ Gong - Hepatology Research, 2008 - Wiley Online Library
This study was undertaken to investigate whether plasmacytoid dendritic cells (PDC) are
involved in the generation of a higher proportion of CD4+ and CD25+ regulatory T (Treg) …