Effect of a buffered crystalloid solution vs saline on acute kidney injury among patients in the intensive care unit: the SPLIT randomized clinical trial
Importance Saline (0.9% sodium chloride) is the most commonly administered intravenous
fluid; however, its use may be associated with acute kidney injury (AKI) and increased …
fluid; however, its use may be associated with acute kidney injury (AKI) and increased …
Balanced crystalloids versus saline in the intensive care unit. The SALT randomized trial
Rationale: Saline is the intravenous fluid most commonly administered to critically ill adults,
but it may be associated with acute kidney injury and death. Whether use of balanced …
but it may be associated with acute kidney injury and death. Whether use of balanced …
Balanced crystalloids versus saline in critically ill adults
Background Both balanced crystalloids and saline are used for intravenous fluid
administration in critically ill adults, but it is not known which results in better clinical …
administration in critically ill adults, but it is not known which results in better clinical …
Balanced crystalloids versus saline in critically ill adults: a systematic review and meta-analysis
Background: The optimal resuscitative fluid remains controversial. Objective: To assess the
association between crystalloid fluid and outcomes in critically ill adults. Methods …
association between crystalloid fluid and outcomes in critically ill adults. Methods …
[HTML][HTML] Should chloride-rich crystalloids remain the mainstay of fluid resuscitation to prevent 'pre-renal'acute kidney injury?: con
DN Lobo, S Awad - Kidney international, 2014 - Elsevier
The high chloride content of 0.9% saline leads to adverse pathophysiological effects in both
animals and healthy human volunteers, changes not seen after balanced crystalloids. Small …
animals and healthy human volunteers, changes not seen after balanced crystalloids. Small …
Balanced crystalloid solutions
Intravenous fluid therapy is the most common intervention received by acutely ill patients.
Historically, saline (0.9% sodium chloride) has been the most frequently administered …
Historically, saline (0.9% sodium chloride) has been the most frequently administered …
Balanced crystalloids versus saline in critically ill adults—a systematic review with meta-analysis
Background The comparative efficacy and safety of balanced crystalloid solutions and saline
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …
Effect of intravenous fluid treatment with a balanced solution vs 0.9% saline solution on mortality in critically ill patients: the BaSICS randomized clinical trial
Importance Intravenous fluids are used for almost all intensive care unit (ICU) patients.
Clinical and laboratory studies have questioned whether specific fluid types result in …
Clinical and laboratory studies have questioned whether specific fluid types result in …
Balanced crystalloids versus saline in noncritically ill adults
Background Comparative clinical effects of balanced crystalloids and saline are uncertain,
particularly in noncritically ill patients cared for outside an intensive care unit (ICU). Methods …
particularly in noncritically ill patients cared for outside an intensive care unit (ICU). Methods …
Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults
Context Administration of traditional chloride-liberal intravenous fluids may precipitate acute
kidney injury (AKI). Objective To assess the association of a chloride-restrictive (vs chloride …
kidney injury (AKI). Objective To assess the association of a chloride-restrictive (vs chloride …