RCC2 contributes to tumor invasion and chemoresistance to cisplatin in hepatocellular carcinoma

Q Chen, P Jiang, B Jia, Y Liu, Z Zhang - Human Cell, 2020 - Springer
Tumor metastasis and chemoresistance are the main causes of treatment failure and high
mortality in hepatocellular carcinoma (HCC). Therefore, it is critical to clarify the biological …

[HTML][HTML] RCC1 expression as a prognostic marker in colorectal liver Oligometastases

Y Deng, L Yu, Y Zhao, J Peng, Y Xu… - Pathology and …, 2021 - por-journal.com
Introduction: Regulator of chromatin condensation 1 (RCC1) is a major guanine-nucleotide
exchange factor for Ran GTPase, and it plays key roles in various biological processes …

RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation

N Wu, D Ren, S Li, W Ma, S Hu, Y Jin, S Xiao - BMC cancer, 2018 - Springer
Background Small GTP binding protein Rac1 is a component of NADPH oxidases and is
essential for superoxide-induced cell death. Rac1 is activated by guanine nucleotide …

RCC1 functions as a tumor facilitator in clear cell renal cell carcinoma by dysregulating cell cycle, apoptosis, and EZH2 stability

Y Wu, Z Xu, X Chen, G Fu, J Tian, B Jin - Cancer Medicine, 2023 - Wiley Online Library
Background RCC1 functions as a pivotal guanine nucleotide exchange factor and was
reported to be involved in mitosis, the assembly of the nuclear envelope, nucleocytoplasmic …

[HTML][HTML] Regulator of chromosome condensation 2 modulates cell cycle progression, tumorigenesis, and therapeutic resistance

K Guo, C Zhao, B Lang, H Wang, H Zheng… - Frontiers in molecular …, 2021 - frontiersin.org
Accurate regulation of cell cycle is important for normal tissue development and
homeostasis. RCC2 (Regulator of Chromosome Condensation 2) play a role as …

RCCRT1 is correlated with prognosis and promotes cell migration and invasion in renal cell carcinoma

S Song, Z Wu, C Wang, B Liu, X Ye, J Chen, Q Yang… - Urology, 2014 - Elsevier
Objective To investigate the expression pattern of a novel long noncoding ribonucleic acid
(RNA), RCCRT1, in renal cell carcinoma (RCC) tissues among the patients with various …

A pan‑cancer analysis of RCC2 and its interaction with HMGA2 protein in an in vitro model of colorectal cancer cells

G Gu, Y Wang, Y Shen, Y Ma… - Experimental and …, 2022 - spandidos-publications.com
Regulator of chromosome condensation 2 (RCC2) is highly involved in the development of
tumor malignancies. The underlying mechanisms remain to be elucidated. The present …

Downregulation of CCR1 inhibits human hepatocellular carcinoma cell invasion

X Wu, J Fan, X Wang, J Zhou, S Qiu, Y Yu, Y Liu… - Biochemical and …, 2007 - Elsevier
CC chemokine receptor 1 (CCR1) has an important role in the recruitment of leukocytes to
the site of inflammation. The migration and metastasis of tumor cells shares many similarities …

[HTML][HTML] CCR9 as a prognostic marker and therapeutic target in hepatocellular carcinoma

Z Zhang, C Qin, Y Wu, Z Su, G Xian… - Oncology …, 2014 - spandidos-publications.com
The chemokine receptor CCR9 was recently implicated in tumor biology. In the present
study, our objective was to evaluate the clinical significance and potential role of CCR9 in …

Rcl1 suppresses tumor progression of hepatocellular carcinoma: a comprehensive analysis of bioinformatics and in vitro experiments

Y Jiaze, H Sinan, Y Minjie, Z Yongjie, D Nan… - Cancer Cell …, 2022 - Springer
Background RNA 3'-terminal phosphate cyclase-like protein (Rcl1) is involved in pre-rRNA
processing, but its implication in cancers remains unclear. Methods RCL1 expressions in 21 …