Introduction Human body functions exhibit a circadian rhythm generated in peripheral cells
and synchronized by the suprachiasmatic nucleus (SCN), which mostly is entrained by the …

The molecular clock orchestrates the circadian integration and organization of many aspects
of physiology that correspond with the duration of the rotation of the earth on its axis, ie, 24 …

The highest risk of cardiovascular events is in the morning, which may be associated with
circadian changes in hemostasis. There is a 10% circadian variability in von Willebrand …

Serious adverse cardiovascular events, including myocardial infarction, sudden cardiac
death, and stroke, frequently result from rupture of atherosclerotic plaques with …

The hemostatic system in its multiple components displays an intricate organization in time
which is characterized by circadian (∼ 24-hour), circaseptan (∼ 7-day), menstrual (∼ …

Analysis of the circadian distributions of silent ischemic episodes and myocardial infarction
has revealed a circadian variability with peak event incidences in the morning hours after …

Approximately 35 years ago, it was discovered that spontaneous fibrinolytic activity in blood
showed a sinusoidal variation with a period of 24 h; it increased severalfold during the day …

Growing evidence shows that intrinsic circadian clocks are tightly related to cardiovascular
functions. The diurnal changes in blood pressure and heart rate are well known circadian …

Biological circadian rhythms in living organisms are regulated by molecular clocks. Several
of these clocks are present in blood vessels, peripheral tissues, and immune cells. There is …

Biological rhythms are a universal phenomenon in living organisms and serve to help
organisms adapt within a circadian cycle to the 24-hour-oscillating environment. The …