A stable and replicable neural signature of lifespan adversity in the adult brain
Environmental adversities constitute potent risk factors for psychiatric disorders. Evidence
suggests the brain adapts to adversity, possibly in an adversity-type and region-specific …
suggests the brain adapts to adversity, possibly in an adversity-type and region-specific …
Mismatch or allostatic load? Timing of life adversity differentially shapes gray matter volume and anxious temperament
M Kuhn, R Scharfenort, D Schümann… - Social Cognitive and …, 2016 - academic.oup.com
Traditionally, adversity was defined as the accumulation of environmental events (allostatic
load). Recently however, a mismatch between the early and the later (adult) environment …
load). Recently however, a mismatch between the early and the later (adult) environment …
Cumulative adversity and smaller gray matter volume in medial prefrontal, anterior cingulate, and insula regions
BACKGROUND: Cumulative adversity and stress are associated with risk of psychiatric
disorders. While basic science studies show repeated and chronic stress effects on …
disorders. While basic science studies show repeated and chronic stress effects on …
The impact of psychosocial adversity on brain and behaviour: an overview of existing knowledge and directions for future research
Environmental experiences play a critical role in shaping the structure and function of the
brain. Its plasticity in response to different external stimuli has been the focus of research …
brain. Its plasticity in response to different external stimuli has been the focus of research …
[HTML][HTML] Long-term neural embedding of childhood adversity in a population-representative birth cohort followed for 5 decades
MZ Gehred, AR Knodt, A Ambler, KJ Bourassa… - Biological …, 2021 - Elsevier
Background Childhood adversity has been previously associated with alterations in brain
structure, but heterogeneous designs, methods, and measures have contributed to mixed …
structure, but heterogeneous designs, methods, and measures have contributed to mixed …
An exploration of dimensions of early adversity and the development of functional brain network connectivity during adolescence: Implications for trajectories of …
Different dimensions of adversity may affect mental health through distinct neurobiological
mechanisms, though current supporting evidence consists largely of cross-sectional …
mechanisms, though current supporting evidence consists largely of cross-sectional …
Associations of perceived adverse lifetime experiences with brain structure in UK Biobank participants
DA Gheorghe, C Li, J Gallacher… - Journal of Child …, 2021 - Wiley Online Library
Background Adversity experiences (AEs) are major risk factors for psychiatric illness, and
ample evidence suggests that adversity‐related changes in brain structure enhance this …
ample evidence suggests that adversity‐related changes in brain structure enhance this …
Adult women first exposed to early adversity after 8 years old show attentional bias to threat
C Raymond, MF Marin, V Wolosianski… - Frontiers in Behavioral …, 2021 - frontiersin.org
Exposure to early adversity (EA) is associated with long-lasting dysregulations in cognitive
processes sustained by brain regions that are sensitive to stress hormones: the …
processes sustained by brain regions that are sensitive to stress hormones: the …
[HTML][HTML] No robust evidence for an interaction between early-life adversity and protective factors on global and regional brain volumes
Childhood adversity is associated with brain morphology and poor psychological outcomes,
and evidence of protective factors counteracting childhood adversity effects on neurobiology …
and evidence of protective factors counteracting childhood adversity effects on neurobiology …
The influence of early-life adversity on the coupling of structural and functional brain connectivity across childhood
Early-life adversity (ELA) exposure is suggested to accelerate development. However, the
influence of ELA on neurodevelopmental trajectories has not been assessed directly but …
influence of ELA on neurodevelopmental trajectories has not been assessed directly but …