Introduction The pituitary gland, regulating various hormones, is central in the endocrine
system. As spontaneous recovery from hypopituitarism is rare, and exogenous-hormone …

Pituitary organoids are promising graft sources for transplantation in treatment of
hypopituitarism. Building on development of self-organizing culture to generate pituitary …

Generation of a variety of organs and tissues from human pluripotent stem cells (hPSCs) has
been attempted in vitro. We here present a simple and efficient method for induction of …

Human pluripotent stem cells (hPSCs) provide an unlimited cell source for regenerative
medicine. Hormone-producing cells are particularly suitable for cell therapy, and …

The hypothalamus and pituitary have been identified to play essential roles in maintaining
homeostasis. Various diseases can disrupt the functions of these systems, which can often …

The hypothalamic-pituitary system is essential to maintain life and control systemic
homeostasis, but it is negatively affected by various diseases, leading to serious symptoms …

The hypothalamic-pituitary system is essential for maintaining life and controlling systemic
homeostasis. However, it can be negatively affected by various diseases, resulting in life …

Despite its small size, the pituitary gland plays a central role in the maintenance of normal
homeostasis of most physiological systems through its regulation of the function of other …

Anterior pituitary is critical for endocrine systems. Its hormonal responses to positive and
negative regulators are indispensable for homeostasis. For this reason, generating human …

The pituitary is a major hormone center that secretes systemic hormones responding to
hypothalamus-derived-releasing hormones. Previously, we reported the independent …