HDAC2 counteracts vascular calcification by activating autophagy in chronic kidney disease
G Zhou, P Liu, C Zhang, Q Huang, Z Zhao… - The FASEB …, 2024 - Wiley Online Library
Vascular calcification is a major risk factor for cardiovascular disease mortality, with a
significant prevalence in chronic kidney disease (CKD). Pharmacological inhibition of …
significant prevalence in chronic kidney disease (CKD). Pharmacological inhibition of …
Hdac9 inhibits medial artery calcification through down-regulation of Osterix
Backgrounds Medial artery calcification (MAC) significantly contributes to the increased
cardiovascular death in patients with chronic kidney disease (CKD). Previous genome-wide …
cardiovascular death in patients with chronic kidney disease (CKD). Previous genome-wide …
Histone Deacetylase 9 Contributes to Vascular Calcification in CKD: SA-PO773
L Xiong, Q Xiao, C Rong, Y Tang, L Wang… - Journal of the …, 2022 - journals.lww.com
Background: Vascular calcification (VC) is a serious complication of chronic kidney disease
(CKD). Unfortunately, there is no effective therapy for VC beyond supportive care due to the …
(CKD). Unfortunately, there is no effective therapy for VC beyond supportive care due to the …
HDAC1‐mediated deacetylation of LSD1 regulates vascular calcification by promoting autophagy in chronic renal failure
J Zhou, H Zhou, C Liu, L Huang, D Lu… - Journal of Cellular and …, 2020 - Wiley Online Library
Chronic renal failure (CRF) is commonly associated with various adverse consequences
including pathological vascular calcification (VC), which represents a significant clinical …
including pathological vascular calcification (VC), which represents a significant clinical …
MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification
Objectives: Vascular calcification (VC) is often associated with cardiovascular and metabolic
diseases. However, the molecular mechanisms linking VC to these diseases have yet to be …
diseases. However, the molecular mechanisms linking VC to these diseases have yet to be …
Downregulation of HDAC9 by the ketone metabolite β‐hydroxybutyrate suppresses vascular calcification
Z Lan, A Chen, L Li, Y Ye, Q Liang… - The Journal of …, 2022 - Wiley Online Library
Vascular calcification is an actively regulated process resembling bone formation and
contributes to the cardiovascular morbidity and mortality of chronic kidney disease (CKD) …
contributes to the cardiovascular morbidity and mortality of chronic kidney disease (CKD) …
Downregulation of Histone Deacetylase 9 (HDAC9) is Associated with Vascular Calcification in Diabetic Mice.
SA Benerofe, MA Carrillo‐Sepulveda - The FASEB Journal, 2017 - Wiley Online Library
Vascular complications, including calcification, are some of the major problems faced by
type 2 diabetic (T2DM) patients. In fact, the majority of these diabetic patients will die due to …
type 2 diabetic (T2DM) patients. In fact, the majority of these diabetic patients will die due to …
[HTML][HTML] MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification
DH Kwon, GH Eom, JH Ko, S Shin, H Joung… - Nature …, 2016 - nature.com
Vascular calcification (VC) is often associated with cardiovascular and metabolic diseases.
However, the molecular mechanisms linking VC to these diseases have yet to be elucidated …
However, the molecular mechanisms linking VC to these diseases have yet to be elucidated …
Histone deacetylase 3 plays a critical role in hypertension-induced kidney inflammation and fibrosis
Objective: Hypertension is a major cause of chronic kidney disease. The molecular
mechanisms how hypertension causes kidney disease are not fully understood. In this study …
mechanisms how hypertension causes kidney disease are not fully understood. In this study …
[HTML][HTML] Roles of histone acetylation modifiers and other epigenetic regulators in vascular calcification
Vascular calcification (VC) is characterized by calcium deposition inside arteries and is
closely associated with the morbidity and mortality of atherosclerosis, chronic kidney …
closely associated with the morbidity and mortality of atherosclerosis, chronic kidney …