Enzymes belonging to the glutathione-S-transferase (GST) and cytochrome P450 (CYP)
families are involved in a 2-stage detoxification process of a wide range of environmental …

OBJECTIVE: To examine whether a relationship exists between genetic polymorphisms of
glutathione S-transferase (GST) M1 and T1, CYP1A1∗ 2C, and male factor infertility …

Male infertility is a heterogeneous disorder, with various genetic and environmental factors
that contribute to the impairment of spermatogenesis. Genetic causes are responsible for …

The effects of the GST genes (GSTM1, GSTT1 and GSTP1) on male factor infertility have not
been well elucidated. A case–control study was performed to investigate the association …

PURPOSE: To determine the role of glutathione S-transferases (GSTs; GSTM1, GSTT1, and
GSTP1) gene polymorphisms in susceptibility to male factor infertility. MATERIALS AND …

The aim of this study was to examine whether an association exists between glutathione S‐
transferase Mu‐1 (GSTM1) gene polymorphism and idiopathic male infertility. Forty‐two men …

This study was designed to investigate the association between null polymorphisms of
glutathione S-transferase (GST) M1 and T1 genes and idiopathic male infertility in a Russian …

Background Genes of different pathways regulate spermatogenesis, and the complexity of
the spermatogenic process indicates that polymorphisms or mutations in these genes could …

Inconsistent results of association studies investigated the role of glutathione S–transferase
genes in idiopathic male infertility may be explained by ethnical differences in gene–gene …

Polymorphisms of xenobiotic detoxification genes GSTT1 and GSTM1 and activity of
glutathione system enzymes were studied in men with infertility. The frequency of deletion …