Bromelain mediates apoptosis in HeLa cells via ROS-independent pathway

A Pal, SK Sil - Advances in Traditional Medicine, 2023 - Springer
Several in vitro studies along with some in vivo studies have shown the anti-cancer activity
of bromelain against several types of cancer except cervical cancer. This study is focused to …

Bromelain-induced apoptosis in GI-101A breast cancer cells

S Dhandayuthapani, HD Perez, A Paroulek… - Journal of medicinal …, 2012 - liebertpub.com
Bromelain is a proteolytic enzyme extracted from the stems and the immature fruits of
pineapple that was found to be antitumorigenic in different in vitro models. Bromelain has …

[HTML][HTML] Bromelain: a potent phytomedicine

P Agrawal, P Nikhade, A Patel, N Mankar, S Sedani - Cureus, 2022 - ncbi.nlm.nih.gov
The commercially available protein-digesting enzyme bromelain is derived from the
pineapple fruit or stem. Bromelain from fruit and stems are produced in different ways and …

Properties and therapeutic application of bromelain: a review

R Pavan, S Jain, Shraddha… - Biotechnology research …, 2012 - Wiley Online Library
Bromelain belongs to a group of protein digesting enzymes obtained commercially from the
fruit or stem of pineapple. Fruit bromelain and stem bromelainare prepared differently and …

Mechanism of berberine-induced apoptosis in cervical cancer HeLa cell line

FL MOU, JR DENG - Basic & Clinical Medicine, 2017 - journal11.magtechjournal.com
Objective To study the apoptosis mechanism of HeLa cells induced by berberine (BR).
Methods HeLa cells were treated by different concentration of BR, with different times. CCK …

[PDF][PDF] Bromelain-based chemo-herbal combination effect on human cancer cells: In-vitro study on AGS and MCF7 proliferation and apoptosis

E Raeisi, MH Aazami, SMR Aghamiri… - Current Issues in …, 2020 - sciendo.com
Aim. Chemo-herbal combinations promise new clinical anticancer therapeutic modalities.
The current study investigated and compared the in vitro effects of a bromelain-based …

Cytotoxic effects of bromelain in human gastrointestinal carcinoma cell lines (MKN45, KATO-III, HT29-5F12, and HT29-5M21)

A Amini, A Ehteda, S Masoumi Moghaddam… - OncoTargets and …, 2013 - Taylor & Francis
Background Bromelain is a pineapple stem extract with a variety of therapeutic benefits
arising from interaction with a number of different biological processes. Several preclinical …

[PDF][PDF] Bromelain's Properties and Therapeutic Applications: A Review

I Zalavadiya, T Ganatra - GIS Science Journal, 2022 - researchgate.net
Bromelain is a protein digesting enzyme that can be purchased commercially from the
Ananas comosus (pineapple) fruit or stem. Bromelain from the fruit and bromelain from the …

Solidago virga-aurea extract induced apoptosis of breast cancer cells through FOXO3 mediated bim expression

H Kim, CH Kim, JH Kim, JM Lee, JH Jeon, JY Lee - Cancer Research, 2016 - AACR
Solidago virga-aurea (European goldenrod or woundwort) is an herbaceous perennial plant
of the family Asteraceae. It is used for medical system with astringent, diuretic, antiseptic and …

[PDF][PDF] Rubia cordifolia root extract induces apoptosis in cancer cell line

S Tiwari, R Upadhyaya, R Shroti, ST Upadhyaya - Sci. Secure J, 2012 - researchgate.net
Rubia cordifolia Root Extract Induces Apoptosis in Cancer Cell Line Page 1 All Right
Reserved @ 2012, Science Secure Journals 39 Research Article Rubia cordifolia Root …