Non-syndromic cleft lip with or without cleft palate (NSCLP) is the most common craniofacial
birth defect. The etiology of NSCLP is complex with multiple genes and environmental …

Non-syndromic cleft lip and/or palate (NSCLP) is a common congenital malformation with a
multifactorial model of inheritance. Although several at-risk alleles have been identified, they …

Background Epigenetic data could help identify risk factors for orofacial clefts, either by
revealing a causal role for epigenetic mechanisms in causing clefts or by capturing …

Orofacial clefts are among the most common craniofacial anomalies with multifactorial
etiologies, including genetics and environments. DNA methylation, one of the most …

Aim: To determine if nonsyndromic cleft lip with or without cleft palate (nsCL/P) genetic risk
variants influence liability to nsCL/P through gene regulation pathways, such as those …

Background Isolated orofacial clefts are among the most common congenital birth defects.
Although the underlying biological mechanisms remain largely unknown, clefts are thought …

BACKGROUND Environmental factors contribute to the etiology of cleft palate (CP).
Identification of genes that are methylated during development of the secondary palate will …

Congenital nonsyndromic cleft lip and palate (NSCLP) is one of the most common
malformations worldwide. DNA methylation has been implicated in many diseases …

Cleft lip with or without cleft palate (CL/P) is a common human birth defect whose etiologies
remain largely unknown. Several studies have demonstrated that periconceptional …

Background: The pathogenicity of cleft lip (CL) is pretty complicated since it is influenced by
the interaction of environment and genetic factors. The purpose of this study was to conduct …