Carbon monoxide and its role in human physiology: a brief historical perspective
K Kashfi, KK Patel - Biochemical Pharmacology, 2022 - Elsevier
Carbon monoxide is a molecule with notoriety in modern culture and extensive
documentation regarding its toxic physiological effects, long predating its formal discovery in …
documentation regarding its toxic physiological effects, long predating its formal discovery in …
Carbon monoxide is not always a poison gas for human organism: Physiological and pharmacological features of CO
B Olas - Chemico-biological interactions, 2014 - Elsevier
Carbon monoxide (CO) is an odorless, colorless and non-irritating gas. Even a small amount
of CO exposure is possibly associated with specific toxic effects. CO is also produced …
of CO exposure is possibly associated with specific toxic effects. CO is also produced …
Carbon Monoxide as a Potential Therapeutic Agent: A Molecular Analysis of Its Safety Profiles
Carbon monoxide (CO) is endogenously produced in mammals, with blood concentrations
in the high micromolar range in the hemoglobin-bound form. Further, CO has shown …
in the high micromolar range in the hemoglobin-bound form. Further, CO has shown …
Carbon monoxide: endogenous production, physiological functions, and pharmacological applications
Over the last decade, studies have unraveled many aspects of endogenous production and
physiological functions of carbon monoxide (CO). The majority of endogenous CO is …
physiological functions of carbon monoxide (CO). The majority of endogenous CO is …
A brief history of carbon monoxide and its therapeutic origins
CP Hopper, PN Zambrana, U Goebel, J Wollborn - Nitric Oxide, 2021 - Elsevier
It is estimated that 10% of carbon throughout the cosmos is in the form of carbon monoxide
(CO). Earth's earliest prebiotic atmosphere included the trinity of gasotransmitters CO, nitric …
(CO). Earth's earliest prebiotic atmosphere included the trinity of gasotransmitters CO, nitric …
The evolution of carbon monoxide into medicine
LE Otterbein - Respiratory care, 2009 - rc.rcjournal.com
The discovery that carbon monoxide (CO)—a highly publicized toxic gas molecule—can
have powerful benefits and curative effects not only changed how we view CO, but has, with …
have powerful benefits and curative effects not only changed how we view CO, but has, with …
Biological and pharmacological properties of carbon monoxide: a general overview
A Bilska-Wilkosz, M Górny, M Iciek - Oxygen, 2022 - mdpi.com
Carbon monoxide (CO) is one of the most common causes of inhalation poisoning
worldwide. However, it is also well known that CO is produced endogenously in the heme …
worldwide. However, it is also well known that CO is produced endogenously in the heme …
Carbon monoxide: a critical quantitative analysis and review of the extent and limitations of its second messenger function
DG Levitt, MD Levitt - Clinical pharmacology: Advances and …, 2015 - Taylor & Francis
Endogenously produced carbon monoxide (CO) is commonly believed to be a ubiquitous
second messenger involved in a wide range of physiological and pathological responses …
second messenger involved in a wide range of physiological and pathological responses …
Carbon monoxide in biology and medicine
SW Ryter, LE Otterbein - Bioessays, 2004 - Wiley Online Library
Carbon monoxide (CO), a product of organic oxidation processes, arises in vivo during
cellular metabolism, most notably heme degradation. CO binds to the heme iron of most …
cellular metabolism, most notably heme degradation. CO binds to the heme iron of most …
Carbon monoxide and human disease
D Morse, J Sethi - Antioxidants and Redox Signaling, 2002 - liebertpub.com
Carbon monoxide is produced endogenously in humans through the breakdown of
hemoglobin by heme oxygenase. Although originally thought to be a superfluous by-product …
hemoglobin by heme oxygenase. Although originally thought to be a superfluous by-product …