Context Germline testing (GT) is increasingly impacting prostate cancer (PCa) management
and screening, with direct effects in urology, medical oncology, and radiation oncology. The …

Objective To review the current status of germline and somatic (tumour) genetic testing for
prostate cancer (PCa), and its relevance for clinical practice. Methods A narrative synthesis …

Background Germline and tumour genetic testing in prostate cancer (PCa) is becoming
more broadly accepted, but testing indications and clinical consequences for carriers in …

Background Germline testing is recommended for all men with metastatic prostate cancer
(PCa), and for some with localized PCa meeting specific histologic or family history criteria …

Background Germline genetic testing increasingly identifies advanced prostate cancer
(PCa) patients who are candidates for precision therapies. The Prostate Cancer Clinical …

Genetic testing for prostate cancer is rapidly growing and is increasingly being driven by
precision medicine. Rates of germline pathogenic variants have been reported in up to 15 …

Inherited genetic mutations can significantly increase the risk for prostate cancer (PC), may
be associated with aggressive disease and poorer outcomes, and can have hereditary …

Most criteria for genetic testing for prostate cancer susceptibility require a prior diagnosis of
prostate cancer, in particular cases with metastatic disease are selected. Advances in the …

Purpose: Until recently the role of germline genetics in prostate cancer care was not well
defined. While important questions remain, we reviewed the current understanding of …

Abstract Purpose of Review This review summarizes recent advances in prostate cancer
(PCa) genetics. Recent Findings Upwards of 20% of metastatic castration-resistant prostate …