Background: Introduction of pro-angiogenic cells into tissue-engineered (TE) constructs
(prevascularisation) is a promising approach to overcome delayed neovascularisation of …

In severe cases of peripheral arterial disease, tissue loss can occur and the use of vascular
grafts can be necessary. However, currently, there are no suitable substitutes for application …

Tissue engineering is based on the association of cultured cells with structural matrices and
the incorporation of signaling molecules for inducing tissue regeneration. Despite its …

Despite unprecedented advancement in the field of tissue engineering (TE), only a few
engineered tissues-namely skin, cartilage and bladder-have achieved clinical success …

The strategy of vascular tissue engineering is to create a vascular substitute by combining
autologous vascular cells with a tubular-shaped biodegradable scaffold. We have previously …

If endothelial progenitor cells (EPCs), which circulate in blood flow, are captured on the
luminal surface of an implanted artificial graft and sooner or later proliferate to form a fully …

Vascular differentiation of stem cells and matrix component production on electrospun
tubular scaffolds is desirable to engineer blood vessels. The mouse embryonic multipotent …

Objective: The purpose of this study was to test the hypothesis that explanted perfused
arteries can serve as the initial endothelial cell culture source to evaluate the onset of …

Tissue engineering presents a promising solution for regenerative medicine and the
success depends on the supply of oxygen/nutrients to the cells by rapid vascularization …

To date, there has been little investigation of biodegradable tissue engineered arterial grafts
(TEAG) using clinically relevant large animal models. The purpose of this study is to explore …