Methamphetamine exacerbates pathophysiology of traumatic brain injury at high altitude. Neuroprotective effects of nanodelivery of a potent antioxidant compound H …

HS Sharma, JV Lafuente, L Feng, DF Muresanu… - Progress in brain …, 2021 - Elsevier
Military personnel are often exposed to high altitude (HA, ca. 4500–5000 m) for combat
operations associated with neurological dysfunctions. HA is a severe stressful situation and …

Exacerbation of methamphetamine neurotoxicity in cold and hot environments: neuroprotective effects of an antioxidant compound H-290/51

HS Sharma, EA Kiyatkin, R Patnaik, JV Lafuente… - Molecular …, 2015 - Springer
In this study, we examined the influence of cold and hot environments on methamphetamine
(METH) neurotoxicity in both drug-naive rats and animals previously exposed to different …

Cold environment exacerbates brain pathology and oxidative stress following traumatic brain injuries: potential therapeutic effects of nanowired antioxidant compound …

A Sharma, DF Muresanu, JV Lafuente… - Molecular …, 2018 - Springer
The possibility that traumatic brain injury (TBI) occurring in a cold environment exacerbates
brain pathology and oxidative stress was examined in our rat model. TBI was inflicted by …

Nanodelivery of oxiracetam enhances memory, functional recovery and induces neuroprotection following concussive head injury

F Niu, A Sharma, Z Wang, L Feng, DF Muresanu… - Progress in Brain …, 2021 - Elsevier
Military personnel are the most susceptible to concussive head injury (CHI) caused by
explosion, blast or missile or blunt head trauma. Mild to moderate CHI could induce lifetime …

Nanowired drug delivery of antioxidant compound H-290/51 enhances neuroprotection in hyperthermia-induced neurotoxicity

DF Muresanu, A Sharma, Z Ryan Tian… - CNS & Neurological …, 2012 - ingentaconnect.com
Nanoparticles from the environment or through industrial sources can induce profound
alterations in human health, often leading to brain dysfunction. However, it is still unclear …

[HTML][HTML] Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury

JW Skovira, J Wu, JJ Matyas, A Kumar… - Journal of …, 2016 - Springer
Background Traumatic brain injury (TBI) patients in military settings can be exposed to
prolonged periods of hypobaria (HB) during aeromedical evacuation. Hypobaric exposure …

Nanodelivery of histamine H3 receptor inverse agonist BF-2649 with H3 receptor antagonist and H4 receptor agonist clobenpropit induced neuroprotection is …

AD Buzoianu, A Sharma, DF Muresanu… - International Review …, 2023 - europepmc.org
Military personnel are often victims of spinal cord injury resulting in lifetime disability and
decrease in quality of life. However, no suitable therapeutic measures are still available to …

[HTML][HTML] Impact of gulf war toxic exposures after mild traumatic brain injury

S Ferguson, R McCartan, M Browning… - Acta Neuropathologica …, 2022 - Springer
Chemical and pharmaceutical exposures have been associated with the development of
Gulf War Illness (GWI), but how these factors interact with the pathophysiology of traumatic …

Repeated forced swim exacerbates methamphetamine-induced neurotoxicity: neuroprotective effects of nanowired delivery of 5-HT3-Receptor antagonist …

JV Lafuente, A Sharma, DF Muresanu… - Molecular …, 2018 - Springer
The possibility that stress associated with chronic forced swim (FS) may exacerbate
methamphetamine (METH) neurotoxicity was examined in a rat model. Rats were subjected …

Breakdown of blood-brain and blood-spinal cord barriers during acute methamphetamine intoxication: role of brain temperature

EA Kiyatkin, HS Sharma - CNS & Neurological Disorders …, 2016 - ingentaconnect.com
Methamphetamine (METH) is a powerful and often-abused stimulant with potent addictive
and neurotoxic properties. While it is generally believed that structural brain damage …