Acquired heat acclimation in rats subjected to physical exercise under environmental heat stress alleviates brain injury caused by exertional heat stroke

X Li, F Xv, L Ma, L Xing, J Zhao, W Zhi, L Wang… - Brain Research, 2023 - Elsevier
Background Exertional heatstroke (EHS) is an emergency with a high mortality rate,
characterized by central nervous system dysfunctions. This study aims to establish a Heat …

Bioenergetics failure and oxidative stress in brain stem mediates cardiovascular collapse associated with fatal methamphetamine intoxication

FCH Li, JC Yen, SHH Chan, AYW Chang - PloS one, 2012 - journals.plos.org
Background Whereas sudden death, most often associated with cardiovascular collapse,
occurs in abusers of the psychostimulant methamphetamine (METH), the underlying …

Nanowired Delivery of Curcumin Attenuates Methamphetamine Neurotoxicity and Elevates Levels of Dopamine and Brain-Derived Neurotrophic Factor

I Ottonelli, A Sharma, B Ruozi, G Tosi… - … in Nanomedicine in …, 2023 - Springer
Curcumin is a well-known antioxidant used as traditional medicine in China and India since
ages to treat variety of inflammatory ailments as a food supplement. Curcumin has antitumor …

The Effect of High-Altitude Hypoxia on Neuropsychiatric Functions

B Liu, M Yuan, M Yang, H Zhu… - High Altitude Medicine & …, 2024 - liebertpub.com
Liu, Bo, Minlan Yuan, Mei Yang, Hongru Zhu, and Wei Zhang. The effect of high-altitude
hypoxia on neuropsychiatric functions. High Alt Med Biol. 25: 26–41, 2024. Background: In …

Hypertension exacerbates cerebrovascular oxidative stress induced by mild traumatic brain injury: protective effects of the mitochondria-targeted antioxidative peptide …

A Czigler, L Toth, N Szarka, G Berta, K Amrein… - Journal of …, 2019 - liebertpub.com
Traumatic brain injury (TBI) induces cerebrovascular oxidative stress, which is associated
with neurovascular uncoupling, autoregulatory dysfunction, and persisting cognitive decline …

[HTML][HTML] Neuronal and vascular deficits following chronic adaptation to high altitude

NP Cramer, A Korotcov, A Bosomtwi, X Xu… - Experimental …, 2019 - Elsevier
We sought to understand the mechanisms underlying cognitive deficits that are reported to
affect non-native subjects following their prolonged stay and/or work at high altitude (HA) …

Exposure to hyperbaric O2 levels leads to blood-brain barrier breakdown in rodents

YM Danino, R Rabinovitz, I Kirshenboim… - Fluids and Barriers of …, 2024 - Springer
Introduction Hyperbaric oxygen has been used as a medical treatment tool in hyperbaric
chambers and is an integral part of professional and combat divers' activity. In extreme …

Memantine ameliorates cognitive impairment induced by exposure to chronic hypoxia environment at high altitude by inhibiting excitotoxicity

W Ji, Y Zhang, J Luo, Y Wan, J Liu, RL Ge - Life Sciences, 2021 - Elsevier
Aims Memantine is a non-competitive antagonist of glutamatergic NMDA receptor that is
mainly used in the treatment of Alzheimer's disease. The excitatory toxicity mediated by …

Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury

Q Zhao, F Xie, D Guo, J He, T Yao, P Zhao, S Pan… - Brain research, 2020 - Elsevier
Traumatic brain injury (TBI) is a major cause of mortality and disability worldwide. To date,
therapies to treat any forms of TBI are still limited. Recent studies have demonstrated the …

[HTML][HTML] Differences in cognitive function of rats with traumatic brain injuries following hyperbaric oxygen therapy

X Zhang, X Wang, X Sun, X Sun, Y Zhang… - … Medical Journal of …, 2016 - ncbi.nlm.nih.gov
Background Hyperbaric oxygen (HBO) is a historical therapeutic option in the treatment of
various types of brain damage. At present, clinical treatment of hypoxic-ischemic injury is …