Expression of adipogenic transcription factors, peroxisome proliferator-activated receptor gamma co-activator 1, IL-6 and CD45 in subcutaneous adipose tissue in …

K Kannisto, J Sutinen, E Korsheninnikova, RM Fisher… - Aids, 2003 - journals.lww.com
Objective: To determine the expressions of multiple genes in the subcutaneous adipose
tissue of HIV-positive, highly active antiretroviral therapy (HAART)-treated patients with and …

Effects of rosiglitazone on gene expression in subcutaneous adipose tissue in highly active antiretroviral therapy-associated lipodystrophy

J Sutinen, K Kannisto… - American Journal …, 2004 - journals.physiology.org
Highly active antiretroviral therapy (HAART) has improved the prognosis of human
immunodeficiency virus (HIV)-infected patients but is associated with severe adverse events …

HIV-1 infection alters gene expression in adipose tissue, which contributes to HIV-1/HAART-associated lipodystrophy

M Giralt, P Domingo, JP Guallar… - Antiviral …, 2006 - journals.sagepub.com
Background The aetiopathogenic bases of HIV-1-/highly active antiretroviral treatment
(HAART)-associated lipodystrophy (HALS) are poorly known, but this syndrome indicates …

Adipose tissue inflammation and liver fat in patients with highly active antiretroviral therapy-associated lipodystrophy

K Sevastianova, J Sutinen, K Kannisto… - American Journal …, 2008 - journals.physiology.org
In this cross-sectional study, we sought to determine whether gene expression of
macrophage markers and inflammatory chemokines in lipoatrophic subcutaneous …

Differentially altered molecular signature of visceral adipose tissue in HIV-1–associated lipodystrophy

JM Gallego-Escuredo, J Villarroya… - JAIDS Journal of …, 2013 - journals.lww.com
Objective: Lipodystrophy in HIV-1–infected antiretroviral-treated patients is often associated
with opposite alterations in adipose tissue depots as follows: lipoatrophy of subcutaneous …

Altered fat differentiation and adipocytokine expression are inter-related and linked to morphological changes and insulin resistance in HIV-1-infected lipodystrophic …

V Jan, P Cervera, M Maachi, M Baudrimont… - Antiviral …, 2004 - journals.sagepub.com
Objective To achieve a better understand of the pathophysiology of HIV-related lipoatrophy,
we compared the mRNA expression of adipocytokines in fat samples from patients and …

Genetic polymorphisms differently influencing the emergence of atrophy and fat accumulation in HIV-related lipodystrophy

BZ Poma, A Riva, M Nasi, P Cicconi, V Broggini… - Aids, 2008 - journals.lww.com
Objective and design: The present study aims at evaluating the influence of genetic
polymorphisms on antiretroviral therapy (ART)-associated lipodystrophy. We included in the …

HIV antiretroviral treatment alters adipokine expression and insulin sensitivity of adipose tissue in vitro and in vivo

C Lagathu, M Kim, M Maachi, C Vigouroux, P Cervera… - Biochimie, 2005 - Elsevier
HIV-1-infected patients on antiretroviral therapy frequently develop a lipodystrophy
syndrome, characterized by peripheral lipoatrophy and visceral fat redistribution associated …

Microarray analysis during adipogenesis identifies new genes altered by antiretroviral drugs

M Pacenti, L Barzon, F Favaretto, K Fincati, S Romano… - Aids, 2006 - journals.lww.com
Objective: To elucidate the pathogenesis of HAART-associated lipodystrophy, by
investigating the effects of antiretroviral drugs on adipocyte differentiation and gene …

[HTML][HTML] Antiretroviral‐Related Adipocyte Dysfunction and Lipodystrophy in HIV‐Infected Patients: Alteration of the PPARγ‐Dependent Pathways

M Caron, C Vigouroux, JP Bastard, J Capeau - PPAR research, 2009 - Wiley Online Library
Lipodystrophy and metabolic alterations are major complications of antiretroviral therapy in
HIV‐infected patients. In vitro studies using cultured murine and human adipocytes revealed …