Abstract Background & Aims Inadequate adrenal function has been described in patients
with cirrhosis. We investigated (i) the pituitary–adrenal axis at different clinical stages and (ii) …

Abstract Background and Aim: We investigated:(i) the association between severity of
cirrhosis and serum levels of free cortisol (SFC) and total cortisol (STC), measured before …

Background & Aims Measurements of serum levels of total cortisol can overestimate the
prevalence of adrenal dysfunction in patients with cirrhosis because they have low …

Background. The clinical impact of relative adrenal insufficiency (AI) on patients with stable
decompensated cirrhosis (DeCi) has not been yet elucidated. Aim. Explore the association …

Background Adrenal insufficiency is often present in cirrhosis. We hypothesize that a
prolonged adrenocorticotropic hormone (ACTH) stimulus can restore cellular capacity of …

ABSTRACT Background/Aims: Reports on adrenal insufficiency (AI) are unexpectedly high
in cirrhosis, and the diagnosis of this condition remains a challenge. We aimed to define the …

Background & Aims Hepatic enzymes play a major role in the metabolic elimination of
cortisol, and reduced rates of cortisol clearance have been consistently observed in patients …

Background Adrenal insufficiency (AI), also known as hepato-adrenal syndrome, is a well-
known entity in cirrhotic patients. However, factors associated with AI and its effect on …

Background The short synacthen test (SST) is used to investigate patients with suspected
hypothalamus–pituitary–adrenal (HPA) axis pathology. A rise of serum total cortisol (total …

BACKGROUND & AIMS: Adrenal insufficiency (AI) is reported in critically ill patients with
cirrhosis and is associated with increased mortality. It is unclear if AI is an underlying …