Intramuscularly Administered PLGA Microparticles for Sustained Release of Rivastigmine: In Vitro, In Vivo and Histological Evaluation

J Avendaño-Godoy, A Miranda, S Mennickent… - Journal of …, 2023 - Elsevier
Rivastigmine is an acetylcholinesterase (AchE) and butyrylcholinesterase (BchE) inhibitor
drug approved by the US Food and Drug Administration (FDA) for the treatment of mild to …

In situ-forming microparticles for controlled release of rivastigmine: in vitro optimization and in vivo evaluation

M Haider, I Elsayed, IS Ahmed, AR Fares - Pharmaceuticals, 2021 - mdpi.com
In this work, sucrose acetate isobutyrate (SAIB) and polylactic co-glycolic acid (PLGA) were
used alone or in combination as a matrix-former (MF) to prepare long-acting injectable …

Rivastigmine-loaded L-lactide-depsipeptide polymeric nanoparticles: decisive formulation variable optimization

K Pagar, P Vavia - Scientia Pharmaceutica, 2013 - mdpi.com
The main aim of the investigation was to explore a novel L-lactide-depsipeptide copolymer
for the development of rivastigmine-loaded polymeric nanoparticles. L-lactide-depsipeptide …

Preparation of a reproducible long-acting formulation of risperidone-loaded PLGA microspheres using microfluidic method

E Jafarifar, M Hajialyani, M Akbari… - Pharmaceutical …, 2017 - Taylor & Francis
The aim of the present study is to prepare risperidone-loaded poly lactic-co-glycolic acid
(PLGA) microspheres within microfluidic system and to achieve a formulation with uniform …

Influence of drying processes on the structures, morphology and in vitro release profiles of risperidone-loaded PLGA microspheres

Z Wu, M Zhao, W Zhang, Z Yang, S Xu… - Journal of …, 2019 - Taylor & Francis
The purpose of this study was to investigate the influences of drying methods on the
risperidone (RIS) release profiles of RIS-loaded PLGA microspheres. These microspheres …

Effects of formulation parameters on encapsulation efficiency and release behavior of thienorphine loaded PLGA microspheres

Y Yang, Y Gao, X Mei - Pharmaceutical Development and …, 2013 - Taylor & Francis
To develop a long-acting injectable thienorphine biodegradable poly (d, l-lactide-co-
glycolide)(PLGA) microsphere for the therapy of opioid addiction, the effects of formulation …

In vitro evaluation of sustained release of risperidone‐loaded microspheres fabricated from different viscosity of PLGA polymers

Q Shang, A Zhang, Z Wu, S Huang… - Polymers for advanced …, 2018 - Wiley Online Library
The aim of this study was to fabricate different risperidone (RIS)–loaded poly (lactic‐co‐
glycolic acid) microspheres (PLGA MS) with various viscosity of PLGA polymers and …

An accelerated release method of risperidone loaded PLGA microspheres with good IVIVC

X Hu, J Zhang, X Tang, M Li, S Ma, C Liu… - Current drug …, 2018 - ingentaconnect.com
Background: A long release period lasting several days or several weeks is always needed
and thereby it is tedious and time consuming to screen formulations of such microspheres …

Preparation andin vivo evaluation of huperzine A-loaded PLGA microspheres

XD Fu, YL Gao, QN Ping, T Ren - Archives of pharmacal research, 2005 - Springer
Huperzine A-loaded microspheres composed of poly (D, L-lactide-co-glycolide) were
prepared by an O/W emulsion solvent evaporation method. The characterization of the …

Development of risperidone PLGA microspheres

S D'Souza, JA Faraj, S Giovagnoli… - Journal of Drug …, 2014 - Wiley Online Library
The aim of this study was to design and evaluate biodegradable PLGA microspheres for
sustained delivery of Risperidone, with an eventual goal of avoiding combination therapy for …