As a nuclear transcription factor, the androgen receptor (AR) plays a crucial role not only in
normal male sexual differentiation and growth of the prostate, but also in benign prostatic …

Anti-androgens are an assorted group of drugs and compounds that reduce the levels or
activity of androgen hormones within the human body. Disease states in which this is …

It has been strongly suggested that androgens and the cognate receptor (AR) may play
important roles in the development and progression of prostate cancer. The AR is a …

Emerging data are suggesting that estrogens, in addition to androgens, may also be
contributing to the development of prostate cancer (PCa). In view of this notion, agents that …

Prostate cancer is the second leading cause of cancer death in men in United States. It has
been projected that in the year 2001, 198,100 new cases will be diagnosed (American …

Androgen receptor (AR) functions as a transcriptional factor for the development and
progression of prostate cancer. Resveratrol is known to inhibit the function of AR and to …

Prostate cancer (PCa) represents a major cause of cancer mortality among men in
developed countries. Patients with recurrent disease initially respond to androgen …

Androgen and androgen receptor (AR) signaling are crucial for the genesis of prostate
cancer (PCa), which can often develop into androgen-ligand-independent diseases that are …

Enlargement of prostate, which affects 50% of men aged 60 and 90% of men by age 80, is
commonly referred to as benign prostate hyperplasia (BPH)(Russell & Wilson, 1994). BPH is …

Androgen is a key for the activation of Androgen Receptor (AR) in most of the disease
conditions, however androgen-independent activation of AR is also found in aggressive type …