[HTML][HTML] Platelet-derived growth factor PDGF-AA upregulates connexin 43 expression and promotes gap junction formations in osteoblast cells through p-Akt signaling
T Zuo, Y Liu, M Duan, X Pu, M Huang, D Zhang… - … and Biophysics Reports, 2023 - Elsevier
Gap junctions, which are mainly composed of connexin units, play an indispensable role in
cell morphogenesis, proliferation, migration, adhesion and differentiation of osteoblast …
cell morphogenesis, proliferation, migration, adhesion and differentiation of osteoblast …
PDGF-AA promotes cell-to-cell communication in osteocytes through PI3K/Akt signaling pathway
Y Liu, M Duan, D Guo, S Kan, L Zhang… - Acta Biochimica et …, 2021 - academic.oup.com
Osteocytes are the main sensitive cells in bone remodeling due to their potent functional cell
processes from the mineralized bone matrix to the bone surface and the bone marrow …
processes from the mineralized bone matrix to the bone surface and the bone marrow …
PDGF-AA promotes gap junction intercellular communication in chondrocytes via the PI3K/Akt pathway
S Xu, Y Liu, D Zhang, H Huang, J Li, J Wei… - Connective Tissue …, 2022 - Taylor & Francis
Background Gap junction intercellular communication (GJIC) plays an important role in cell
growth, development and homeostasis. Connexin 43 (Cx43) is an important half-channel …
growth, development and homeostasis. Connexin 43 (Cx43) is an important half-channel …
TGF-β1 facilitates cell–cell communication in osteocytes via connexin43-and pannexin1-dependent gap junctions
W Liu, D Zhang, X Li, L Zheng, C Cui, Y Cui, J Sun… - Cell death …, 2019 - nature.com
Connexins and pannexins are two families of channel forming proteins that are able to pass
small molecules to achieve communication between cells. While connexins have been …
small molecules to achieve communication between cells. While connexins have been …
Transforming growth factor-β1-induced N-cadherin drives cell–cell communication through connexin43 in osteoblast lineage
Y Yang, W Liu, JY Wei, Y Cui, D Zhang… - International journal of …, 2021 - nature.com
Gap junction (GJ) has been indicated to have an intimate correlation with adhesion junction.
However, the direct interaction between them partially remains elusive. In the current study …
However, the direct interaction between them partially remains elusive. In the current study …
PDGFR in PDGF-BB/PDGFR signaling pathway does orchestrates osteogenesis in a temporal manner
F Wang, Y Ye, Z Zhang, W Teng, H Sun, X Chai… - Research, 2023 - spj.science.org
Platelet-derived growth factor-BB (PDGF-BB)/platelet-derived growth factor receptor-β
(PDGFR-β) pathway is conventionally considered as an important pathway to promote …
(PDGFR-β) pathway is conventionally considered as an important pathway to promote …
Transforming growth factor-β1 up-regulates connexin43 expression in osteocytes via canonical Smad-dependent signaling pathway
W Liu, Y Cui, J Sun, L Cai, J Xie, X Zhou - Bioscience reports, 2018 - portlandpress.com
Connexin 43 (Cx43)-mediated gap junctional intercellular communication (GJIC) has been
shown to be important in regulating multiple functions of bone cells. Transforming growth …
shown to be important in regulating multiple functions of bone cells. Transforming growth …
PDGF‐AA guides cell crosstalk between human dental pulp stem cells in vitro via the PDGFR‐α/PI3K/Akt axis
S Xu, J Wei, Y Liu, L Zhang, M Duan, J Li… - International …, 2024 - Wiley Online Library
Aim To explore the influence of PDGF‐AA on cell communication between human dental
pulp stem cells (DPSCs) by characterizing gap junction intercellular communication (GJIC) …
pulp stem cells (DPSCs) by characterizing gap junction intercellular communication (GJIC) …
Prostaglandin promotion of osteocyte gap junction function through transcriptional regulation of connexin 43 by glycogen synthase kinase 3/β-catenin signaling
X Xia, N Batra, Q Shi, LF Bonewald… - … and cellular biology, 2010 - Taylor & Francis
Gap junction intercellular communication in osteocytes plays an important role in bone
remodeling in response to mechanical loading; however, the responsible molecular …
remodeling in response to mechanical loading; however, the responsible molecular …
Platelet-derived growth factor-BB regenerates functional periodontal ligament in the tooth replantation
K Komatsu, H Ideno, T Shibata, K Nakashima… - Scientific Reports, 2022 - nature.com
Tooth ankylosis is a pathological condition of periodontal ligament (PDL) restoration after
tooth replantation. Platelet-derived growth factor-BB (PDGF-BB) has been proposed as a …
tooth replantation. Platelet-derived growth factor-BB (PDGF-BB) has been proposed as a …
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