Surface modified PAMAM dendrimers with gallic acid inhibit, cell proliferation, cell migration and inflammatory response to augment apoptotic cell death in human …
K Priyadarshi, K Shirsath, NB Waghela… - Journal of …, 2021 - Taylor & Francis
To overcome the obstacle of anti-cancer therapy significant attention has been drawn for
improving drug delivery system. Since recent past, different approaches were applied using …
improving drug delivery system. Since recent past, different approaches were applied using …
Biological activity of dendrimer–methylglyoxal complexes for improved therapeutic efficacy against malignant cells
The clinical application of methylglyoxal (MG, a normal human metabolite) for cancer
therapy is limited by its facile enzymatic degradation. The present investigation was aimed at …
therapy is limited by its facile enzymatic degradation. The present investigation was aimed at …
Gadobutrol-dendrimer effects on metastatic and apoptotic gene expression
A Kebriaezadeh, S Ashrafi, R Rasouli… - Advances in nano …, 2016 - techno-press.org
Dendrimers are one of the most appropriate nanocaries for imaging moieties in imaging
applications. The purpose of this study was the evalution of cytotoxicity and inducing …
applications. The purpose of this study was the evalution of cytotoxicity and inducing …
Surface modified dendrimers: synthesis and characterization for cancer targeted drug delivery
A Sharma, SP Gautam, AK Gupta - Bioorganic & medicinal chemistry, 2011 - Elsevier
Dendrimers represents a highly branched three-dimensional structure that provides a high
degree of surface functionality and versatility. PAMAM dendrimers are used as well-defined …
degree of surface functionality and versatility. PAMAM dendrimers are used as well-defined …
[HTML][HTML] Modified carboxyl-terminated PAMAM dendrimers as great cytocompatible nano-based drug delivery system
MT Vu, LG Bach, DC Nguyen, MN Ho… - International journal of …, 2019 - mdpi.com
Polyamidoamine (PAMAM) dendrimers are extensively researched as potential drug
delivery system thanks to their desirable features such as controlled and stable structures …
delivery system thanks to their desirable features such as controlled and stable structures …
Silver nanoparticles formulation of Marrubium alysson L. phenolic extract potentiates cytotoxicity through apoptosis with molecular docking study as Bcl-2 inhibitors
Crude or semi-purified extracts of plants can play a significant role as antitumor agents. They
were used as stabilizing and reducing agents in the preparation of silver nanoparticles …
were used as stabilizing and reducing agents in the preparation of silver nanoparticles …
Chitosan nano-vehicles as biocompatible delivering tools for a new Ag (I) curcuminoid-Gboxin analog complex in cancer and inflammation therapy
SEI Elbehairi, LA Ismail, MY Alfaifi… - International Journal of …, 2020 - Elsevier
A novel anticancer and anti-inflammatory agent based on hybrid curcuminoid-Gboxin
analog (FLLL49-GbA) and its macromolecular silver (I) complex (Ag (I) FLLL49-GbA) have …
analog (FLLL49-GbA) and its macromolecular silver (I) complex (Ag (I) FLLL49-GbA) have …
[HTML][HTML] Deguelin and paclitaxel loaded PEG-PCL nano-micelles for suppressing the proliferation and inducing apoptosis of breast cancer cells
Y Wang, Y Lan, L Wu, S Zhang, Q Su… - Frontiers in Bioscience …, 2024 - imrpress.com
Background: Deguelin (DGL) is a natural flavonoid reported to exhibit antitumor effects in
breast cancer (BC). PEG-PCL (Polyethylene Glycol-Polycaprolactone), as polymeric …
breast cancer (BC). PEG-PCL (Polyethylene Glycol-Polycaprolactone), as polymeric …
[HTML][HTML] Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
H Kheraldine, I Gupta, H Alhussain, A Jabeen… - Computational and …, 2021 - Elsevier
HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–
25% of the total cases. It is characterized by aggressive behavior and treatment resistance …
25% of the total cases. It is characterized by aggressive behavior and treatment resistance …
Peganum harmala Alkaloids and Tannic Acid Encapsulated in PAMAM Dendrimers: Improved Anticancer Activities as Compared to Doxorubicin
HMES Azzazy, AM Sawy, A Abdelnaser… - ACS Applied Polymer …, 2022 - ACS Publications
pH-responsive dual-loaded nanoplatforms based on polyamidoamine dendrimer with a
hydroxyl-terminated surface (PAMAM–OH), generations 3, 4, and 5 (G3, G4, and G5 …
hydroxyl-terminated surface (PAMAM–OH), generations 3, 4, and 5 (G3, G4, and G5 …