A malignant tumor has ability to invade the nearby tissues and colonize distant sites
(organs) through the lymphatic/vascular system. From intravasation of cancer cells into the …

Motility is an inherent characteristic of living cells manifesting cell migration, a fundamental
mechanism of survival and development. In unicellular organisms, cell migration is needed …

Cancer Morbidity and mortality result from invasive and metastatic spread. Currently, no
therapies are aimed at the underlying mechanisms that enable this progression due to only …

Heterotypic cell–cell adhesion in the near wall region under dynamic shear forces has been
studied. In particular, we focus on neutrophil (PMN)–melanoma cell emboli formation in a …

Mechanical stimuli such as forces, fluid shear stresses and pressures play a role in the
migration of cancer cells through the endothelial monolayer of blood vessels. In the …

Cancer patients have a shorter life expectancy because of metastasis, which is the dynamic
chain of events that leads to the spread of tumour cells to distant places inside the body …

Cell migration is an essential systemic behavior, tightly regulated, of all living cells endowed
with directional motility that is involved in the major developmental stages of all complex …

Cancer is a highly heterogeneous disease whose molecular basis (genes, proteins,
signaling networks, etc) has been well examined through many years of basic and clinical …

Most cancer-related deaths are caused by the ability of cancer cells to metastasize. This
process includes the dissemination of cancer cells from the primary tumor side and their …

Over the past several decades, scientists have gained a deeper understanding of cancer
biology, which has translated to improved disease detection and treatment in the clinic. Still …