Objective The long-term outcome of non-functioning pituitary adenoma (NFPA) patients is
not clearly established, probably due to the low annual incidence and prolonged natural …

Context Pituitary carcinoma is a rare and aggressive malignancy with a poor prognosis and
few effective treatment options. Case A 35-year-old woman presented with an aggressive …

Pituitary adenomas are considered benign tumors, but approximately 10% of them can have
an aggressive behavior and more rarely (0.2%) can present metastasis, being classified as …

Pituitary carcinomas are rare and neurosurgically challenging lesions, as they commonly
relapse after surgical removal. Their prognosis is dismal due to their limited response to …

Pituitary adenomas are one of the most common primary central nervous system tumors and
have an estimated prevalence of 17%. Approximately half of pituitary adenomas secrete …

Adenohypophyseal tumors, which were recently renamed pituitary neuroendocrine tumors
(PitNET), are mostly benign, but may present various behaviors: invasive,“aggressive” and …

The 4th edition of the World Health Organization (WHO) classification of endocrine tumors
has been recently released. In this new edition, major changes are recommended in several …

Clinically NFPA is currently the preferred term for designing all the pituitary adenomas which
are not hormonally active (in other words, not associated with clinical syndromes such as …

The tumor microenvironment (TME), the complex environment in which tumors develop, has
been increasingly targeted for cancer treatment in recent years. Aggressive pituitary tumors …

Pituitary carcinomas, defined as distant metastases of a pituitary neoplasm, are rare; fewer
than 140 reports exist in the English literature. The initial presenting pituitary tumor is usually …