Antibodies against phosphorylcholine and malondialdehyde during the first two years of life

D Thiagarajan, SL Lundström, G Pershagen… - The Journal of …, 2020 - journals.aai.org
Abs against phosphorylcholine (anti-PC) and Abs against malondialdehyde (anti-MDA) may
be protective in chronic inflammation, like atherosclerosis and cardiovascular disease. It is …

Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases

J Frostegård - Metabolites, 2023 - mdpi.com
Atherosclerosis and its main consequence, cardiovascular disease (CVD) are nowadays
regarded as chronic inflammatory disease conditions, and CVD is the main cause of death …

IgM-antibodies against phosphorylcholine in mothers and normal or low birth weight term newborn infants

AG Frostegård, BG Sjöberg, J Frostegård, M Norman - PloS one, 2014 - journals.plos.org
Objective To determine levels of athero-protective IgM antibodies against phosphorylcholine
in mothers and term-born normal or low birth weight infants. Approach Twenty three mother …

IgM antibodies against malondialdehyde and phosphorylcholine are together strong protection markers for atherosclerosis in systemic lupus erythematosus …

M Rahman, S Sing, Z Golabkesh, R Fiskesund… - Clinical …, 2016 - Elsevier
Objectives Phosphorylcholine (PC) and malondialdehyde (MDA) are generated during lipid
peroxidation and form adducts with proteins as albumin as studied herein. Atherosclerosis …

IgM antibodies against malondialdehyde and phosphorylcholine in different systemic rheumatic diseases

D Thiagarajan, N Oparina, S Lundström, R Zubarev… - Scientific reports, 2020 - nature.com
IgM antibodies against phosphorylcholine (anti-PC) and malondialdehyde (anti-MDA) may
have protective properties in cardiovascular and rheumatic diseases. We here compare …

Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease

J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
Introduction Chronic inflammatory diseases include cardiovascular disease (CVD),
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …

Natural antibodies of newborns recognize oxidative stress-related malondialdehyde acetaldehyde adducts on apoptotic cells and atherosclerotic plaques

C Wang, SP Turunen, O Kummu… - International …, 2013 - academic.oup.com
Malondialdehyde acetaldehyde (MAA) adducts are generated under oxidative stress and
shown to be highly immunogenic. Our aim was to investigate the recognition of MAA adducts …

Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: effects on uptake of oxidized LDL in macrophages as a potential …

U de Faire, J Su, X Hua, A Frostegård, M Halldin… - Journal of …, 2010 - Elsevier
OBJECTIVE: We here determine the role of IgM antibodies against phosphorylcholine (anti-
PC) in prediction of cardiovascular disease (CVD) and on macrophage uptake of Oxidized …

Immunoglobulin G1 antibodies against phosphorylcholine are associated with protection in systemic lupus erythematosus and atherosclerosis: potential underlying …

D Thiagarajan, R Fiskesund, A Frostegård… - ACR open …, 2020 - Wiley Online Library
Objective Immunoglobulin M antibodies against phosphorylcholine (anti‐PC s) may be
protective in atherosclerosis, cardiovascular disease (CVD), and systemic lupus …