A central role of brain mitochondria in regulating and influencing social behaviour is
emerging. In addition to its important roles as the “powerhouses” of the cell, mitochondria …

Here we discuss the role of diverse environmental manipulations affecting cognition with
special regard to psychiatric conditions. We present evidence supporting a direct causal …

Highlights•Mitochondria may contribute to transduce psychological states into biological
recalibrations.•Laboratory methods are available to assess multiple aspects of mitochondrial …

Sociality has profound evolutionary roots and is observed from unicellular organisms to
multicellular animals. In line with the view that social principles apply across levels of …

Social impairment is frequently associated with mitochondrial dysfunction and altered
neurotransmission. Although mitochondrial function is crucial for brain homeostasis, it …

The brain and behavior are under energetic constraints, limited by mitochondrial energy
transformation capacity. However, the mitochondria-behavior relationship has not been …

Background The integration of biological, psychological, and social factors in medicine has
benefited from increasingly precise stress response biomarkers. Mitochondria, a subcellular …

Human and animal studies suggest an intriguing link between mitochondrial diseases and
depression. Although depression has historically been linked to alterations in …

Major depressive disorder (MDD) is a severe mood disorder and frequently associated with
alterations of the immune system characterized by enhanced levels of circulating pro …

Mitochondria play a crucial role in neuronal function, especially in energy production, the
generation of reactive oxygen species, and calcium signaling. Multiple lines of evidence …