Non‐coding RNAs underlying the pathophysiological links between type 2 diabetes and pancreatic cancer: A systematic review

F Dehghanian, Z Azhir, S Khalilian… - Journal of Diabetes …, 2022 - Wiley Online Library
Type 2 diabetes is known as a risk factor for pancreatic cancer (PC). Various genetic and
environmental factors cause both these global chronic diseases. The mechanisms that …

The Link between Diabetes, Pancreatic Tumors, and miRNAs—New Players for Diagnosis and Therapy?

M Kozłowska, A Śliwińska - International Journal of Molecular Sciences, 2023 - mdpi.com
Despite significant progress in medicine, pancreatic cancer is one of the most tardily
diagnosed cancer and is consequently associated with a poor prognosis and a low survival …

Non-coding RNAs in IGF-1R signaling regulation: the underlying pathophysiological link between diabetes and cancer

B Chen, J Li, D Chi, I Sahnoune, S Calin, L Girnita… - Cells, 2019 - mdpi.com
The intricate molecular network shared between diabetes mellitus (DM) and cancer has
been broadly understood. DM has been associated with several hormone-dependent …

Decoding the role of microRNA dysregulation in the interplay of pancreatic cancer and type 2 diabetes

MV Mencucci, MC Abba, B Maiztegui - Molecular and Cellular …, 2023 - Elsevier
This study examines the complex relationship between pancreatic cancer (PC) and type 2
diabetes (T2D) by focusing on the role of microRNAs (miRNAs). miRNAs are small non …

[HTML][HTML] MiRNA dysregulation underlying common pathways in type 2 diabetes and cancer development: an Italian Association of Medical Oncology (AIOM)/Italian …

A Natalicchio, M Montagnani, M Gallo, N Marrano… - ESMO open, 2023 - Elsevier
Increasing evidence suggests that patients with diabetes, particularly type 2 diabetes (T2D),
are characterized by an increased risk of developing different types of cancer, so cancer …

[HTML][HTML] Role of non-coding RNAs in pancreatic cancer: the bane of the microworld

YT Tang, XH Xu, XD Yang, J Hao, H Cao… - World journal of …, 2014 - ncbi.nlm.nih.gov
Our understanding of the mechanisms underlying the development of pancreatic cancer has
been greatly advanced. However, the molecular events involved in the initiation and …

[HTML][HTML] Identification of the shared gene signatures and biological mechanism in type 2 diabetes and pancreatic cancer

Y Hu, N Zeng, Y Ge, D Wang, X Qin, W Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The relationship between pancreatic cancer (PC) and type 2 diabetes mellitus
(T2DM) has long been widely recognized, but the interaction mechanisms are still unknown …

[PDF][PDF] The role of type 2 diabetes in pancreatic Cancer

S George, W Jean-Baptiste, AY Ali, B Inyang, FS Koshy… - Cureus, 2022 - cureus.com
The incidence of type 2 diabetes mellitus (T2DM) and its potential complications, such as
cancers, are increasing worldwide at an astounding rate. There are many factors such as …

[HTML][HTML] Diabetes as a risk factor of pancreatic cancer

D Li, Y Mao - Pancreapedia: The Exocrine Pancreas Knowledge …, 2015 - pancreapedia.org
Pancreatic cancer and diabetes have a complex bidirectional relationship. A large
proportion (varied between 50%–80% by studies) of pancreatic cancer patients have …

[HTML][HTML] Transcriptomic analyses and potential therapeutic targets of pancreatic cancer with concomitant diabetes

T Xu, X Xu, PC Liu, H Mao, S Ju - Frontiers in Oncology, 2020 - frontiersin.org
Background Type 2 diabetes mellitus (T2DM) known as non-insulin-dependent diabetes
mellitus, which is increasingly acknowledged as being associated with an increased risk for …