Understanding apoptotic induction by Sargentodoxa cuneata-Patrinia villosa herb pair via PI3K/AKT/mTOR signalling in colorectal cancer cells using network …

BX Mu, Y Li, N Ye, S Liu, X Zou, J Qian, C Wu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Sargentodoxa cuneata (Sargentodoxa cuneata
(Oliv.) Rehder & EH Wilson, DXT)-Patrinia villosa (Patrinia villosa (Thunb.) Dufr, BJC) …

[HTML][HTML] Network pharmacology and molecular docking study on the mechanism of colorectal cancer treatment using Xiao-Chai-Hu-Tang

J Jin, B Chen, X Zhan, Z Zhou, H Liu, Y Dong - PLoS One, 2021 - journals.plos.org
Background and objective We aimed to predict the targets and signal pathways of Xiao-Chai-
Hu-Tang (XCHT) in the treatment of colorectal cancer (CRC) based on network …

[HTML][HTML] Molecular targets of Chinese herbs: a clinical study of metastatic colorectal cancer based on network pharmacology

H Zhu, J Hao, Y Niu, D Liu, D Chen, X Wu - Scientific reports, 2018 - nature.com
Increasing evidence has shown that Chinese herbal medicine (CHM) has promising
therapeutic effects in colorectal cancer (CRC); however, the active ingredients and potential …

[HTML][HTML] Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of action of Wang Bu Liu Xing …

Y Shi, Y Zhang, J Liu, Y Zhao, W Liu - Journal of Gastrointestinal …, 2023 - ncbi.nlm.nih.gov
Background Colorectal cancer (CRC) is the leading cause of cancer-related death
worldwide. Wang Bu Liu Xing [Semen vaccariae (SV)] is a traditional Chinese medicine …

Mechanism of gypenosides of Gynostemma pentaphyllum inducing apoptosis of renal cell carcinoma by PI3K/AKT/mTOR pathway

H Liu, X Li, Y Duan, JB Xie, XL Piao - Journal of Ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance Gynostemma pentaphyllum (Thunb.) Makino is a
traditional medicine commonly used in China, East Asia and Southeast Asia. In clinic, it is …

[HTML][HTML] Elucidation of the mechanism of action of ailanthone in the treatment of colorectal cancer: integration of network pharmacology, bioinformatics analysis and …

S Ma, X Guo, R Han, Q Meng, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Background: Ailanthone, a small compound derived from the bark of Ailanthus altissima
(Mill.) Swingle, has several anti-tumour properties. However, the activity and mechanism of …

[HTML][HTML] Anti-colorectal cancer of Ardisia gigantifolia Stapf. and targets prediction via network pharmacology and molecular docking study

W Dai, J Yang, X Liu, Q Mei, W Peng, X Hu - … complementary medicine and …, 2023 - Springer
Abstract Background Ardisia gigantifolia Stapf.(AGS), a Chinese folk medicine widely grows
in the south of China and several studies reported that AGS could inhibit the proliferation of …

[HTML][HTML] Exploring the components and mechanism of Solanum nigrum L. for colon cancer treatment based on network pharmacology and molecular docking

JF Chen, SW Wu, ZM Shi, YJ Qu, MR Ding… - Frontiers in …, 2023 - frontiersin.org
Background Solanum nigrum L.(SNL)(Longkui) is a Chinese herb that can be used to treat
colon cancer. The present study explored the components and mechanisms of SNL in …

[HTML][HTML] Uncovering the effects and molecular mechanism of Astragalus membranaceus (Fisch.) Bunge and its bioactive ingredients formononetin and calycosin …

Y Hu, W Zhai, D Tan, H Chen, G Zhang… - Frontiers in …, 2023 - frontiersin.org
Colon cancer is a highly malignant cancer with poor prognosis. Astragalus membranaceus
(Fisch.) Bunge (Huang Qi in Chinese, HQ), a well-known Chinese herbal medicine and a …

[HTML][HTML] Systems pharmacology to reveal multi-scale mechanisms of traditional Chinese medicine for gastric cancer

L Zhang, Y Xiao, R Yang, S Wang, SX Ma, J Liu… - Scientific Reports, 2021 - nature.com
Because of the complex etiology, the treatment of gastric cancer is a formidable challenge
for contemporary medical. The current treatment method focuses on traditional surgical …