Pathology of multiple sclerosis and related inflammatory demyelinating diseases

A Kutzelnigg, H Lassmann - Handbook of clinical neurology, 2014 - Elsevier
This article provides a comprehensive overview of the pathology of multiple sclerosis (MS),
including recent insights into its molecular neuropathology and immunology. It shows that all …

Multiple sclerosis: lessons from neuropathology

CF Lucchinetti, W Brueck, M Rodriguez… - Seminars in …, 1998 - thieme-connect.com
The focus of multiple sclerosis (MS) research has been on attempts to identify the specific
pathogenic mechanism responsible for producing the multifocal central nervous system …

The immunopathology of multiple sclerosis: an overview

H Lassmann, W Brück, CF Lucchinetti - Brain pathology, 2007 - Wiley Online Library
Multiple sclerosis (MS) is traditionally seen as an inflammatory demyelinating disease,
characterized by the formation of focal demyelinated plaques in the white matter of the …

Multiple sclerosis: an immune or neurodegenerative disorder?

BD Trapp, KA Nave - Annu. Rev. Neurosci., 2008 - annualreviews.org
Multiple sclerosis (MS) is an inflammatory-mediated demyelinating disease of the human
central nervous system. The clinical disease course is variable, usually starts with reversible …

A basic overview of multiple sclerosis immunopathology

N Grigoriadis, V Van Pesch - European journal of neurology, 2015 - Wiley Online Library
Multiple sclerosis (MS) is a multi‐component disease characterized by inflammation,
neurodegeneration and failure of central nervous system (CNS) repair mechanisms …

Multiple sclerosis pathology

H Lassmann - Cold Spring Harbor perspectives …, 2018 - perspectivesinmedicine.cshlp.org
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS), which gives rise to focal lesions in the gray and white matter and to …

The pathology of multiple sclerosis

CF Lucchinetti, J Parisi, W Bruck - Neurologic clinics, 2005 - neurologic.theclinics.com
Multiple sclerosis (MS) is a chronic neurologic disease affecting approximately 1 million
adults worldwide and 300,000 Americans [1]. Early illustrations by Carswell in 1838 and …

[HTML][HTML] The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration

SL Hauser, JR Oksenberg - Neuron, 2006 - cell.com
The autoimmune model of multiple sclerosis (MS) pathogenesis provided for many years a
useful but incomplete conceptual framework for understanding the complex array of factors …

The spectrum of multiple sclerosis: new lessons from pathology

W Brück, C Stadelmann - Current opinion in neurology, 2005 - journals.lww.com
The spectrum of multiple sclerosis: new lessons from patholo... : Current Opinion in
Neurology The spectrum of multiple sclerosis: new lessons from pathology : Current …

Progress in understanding the pathophysiology of multiple sclerosis

H Zéphir - Revue neurologique, 2018 - Elsevier
Multiple sclerosis (MS) arises in people who have a genetic susceptibility to environmental
factors and events, which ultimately trigger the disease. It is thought that peripheral immune …