Background: Oxycodone is a strong opioid that acts at mu-and kappa-opioid receptors. It has
pharmacological actions similar to strong opioids, but with a specific pharmacologic profile …

Oxycodone has been in clinical use since 1917. Parenteral oxycodone was used mainly for
the treatment of acute postoperative pain whereas combinations, for example, oxycodone …

Oxycodone is widely used to alleviate moderate-to severe acute pain, It is an effective
analgesic for many types of pain, and is especially useful for paroxysmal spontaneous pain …

Oxycodone is a semi-synthetic opioid with an agonist activity on mu, kappa and delta
receptors. Equivalence with regard to morphine is 1: 2. Its effect commences one hour after …

Oxycodone is a valued opioid analgesic, which may be administered either as the first
strong opioid or when other strong opioids are ineffective. In case of insufficient analgesia …

Abstract Oxycodone (14-hydroxy-7, 8-dihydrocodeinone) is a strong opioid agonist that is
available alone or in combination with mild analgesics. It is suitable for oral administration …

Opioids are widely used as effective analgesic therapy for cancer pain. Despite years of
controversy, their use has been also accepted in chronic non-cancer pain. Oxycodone alone …

A single-dose, analytically blinded, randomized, crossover study was conducted in 22
healthy male volunteers to compare the bioavailability of one 20 mg with two 10 mg …

Optimal pharmacologic management of pain requires selection of the appropriate analgesic
drug, prescription of the appropriate dose, administration of the analgesic by the appropriate …

Introduction: Pain is a likely outcome of any surgical procedure. In several countries the use
of oxycodone has surpassed that of morphine in postoperative pain management. Areas …