Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit
TD Warner, JA Mitchell, G de Nucci… - Journal of …, 1989 - journals.lww.com
We have previously shown that porcine endothelin (ET-1) releases endothelium-derived
relaxing factor (EDRF) in the rat isolated perfused mesentery. Here we show that both ET-1 …
relaxing factor (EDRF) in the rat isolated perfused mesentery. Here we show that both ET-1 …
Inhibition of endothelium-derived relaxing factor enhances endothelin-mediated vasoconstriction.
A Lerman, EK Sandok, FL Hildebrand Jr, JC Burnett Jr - Circulation, 1992 - Am Heart Assoc
BACKGROUND The endothelium possesses the ability to modulate vascular tone by the
release of vasodilators and vasoconstrictors, among them endothelium-derived relaxing …
release of vasodilators and vasoconstrictors, among them endothelium-derived relaxing …
Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins.
TF Lüscher, Z Yang, M Tschudi… - Circulation …, 1990 - Am Heart Assoc
Endothelin-1 is a 21-amino acid endothelial vasoconstrictor peptide that may be the
physiological antagonist of endothelium-derived relaxing factor (EDRF). Endothelin-1 (10 …
physiological antagonist of endothelium-derived relaxing factor (EDRF). Endothelin-1 (10 …
Endothelium-derived relaxing factor modulates endothelin action in afferent arterioles.
S Ito, LA Juncos, N Nushiro, CS Johnson… - …, 1991 - Am Heart Assoc
Endothelin is a potent vasoconstrictor, whereas endothelium-derived relaxing factor (EDRF)
is a potent vasodilator. Both are produced by the endothelium. Although they have been …
is a potent vasodilator. Both are produced by the endothelium. Although they have been …
Does endothelin-1 mediate endothelium-dependent contractions during anoxia?
PM Vanhoutte, W Auch-Schwelk… - Journal of …, 1989 - journals.lww.com
Summary Endothelin-1 (ET-1) is a more potent constrictor of femoral venous than femoral
arterial smooth muscle. By contrast, endothelium-dependent contractions to anoxia are more …
arterial smooth muscle. By contrast, endothelium-dependent contractions to anoxia are more …
Reactivity of endothelin-1 on human and canine large veins compared with large arteries in vitro
In comparison with snake venom sarafotoxins S6, the novel, 21-amino acid peptide,
endothelin may have selective coronary artery vasoconstrictor actions. We examined …
endothelin may have selective coronary artery vasoconstrictor actions. We examined …
Possible role of endothelin in endothelial regulation of vascular tone.
T Masaki - Annual review of pharmacology and toxicology, 1995 - europepmc.org
In vascular beds, a potent vasoconstrictor of endothelin-1 (ET-1) is produced by endothelial
cells and released preferentially to the basal side of endothelial cells. It acts on endothelial …
cells and released preferentially to the basal side of endothelial cells. It acts on endothelial …
Endothelin-1-induced vasoconstriction in humans. Reversal by calcium channel blockade but not by nitrovasodilators or endothelium-derived relaxing factor.
W Kiowski, TF Lüscher, L Linder, FR Bühler - Circulation, 1991 - Am Heart Assoc
The vascular effects of endothelin-1 (ET) in humans were investigated by brachial artery
infusions of ET into 25 healthy volunteers. Forearm blood flow increased from a mean+/-SD …
infusions of ET into 25 healthy volunteers. Forearm blood flow increased from a mean+/-SD …
The mechanism of action of endothelin-1 as compared with other agonists in vascular smooth muscle
A Wallnöfer, SWU Rüegg, C Cauvin - Journal of Cardiovascular …, 1989 - journals.lww.com
The effects of endothelin-1 (ET-1) on tension and membrane potential in rat isolated
mesenteric resistance vessels (MRVs) and on 45 Ca influx, 45 Ca efflux, inositol-1, 4, 5 …
mesenteric resistance vessels (MRVs) and on 45 Ca influx, 45 Ca efflux, inositol-1, 4, 5 …
Oxyhaemoglobin increases the production of endothelin-1 by endothelial cells in culture
TM Cocks, E Malta, SJ King, RL Woods… - European journal of …, 1991 - Elsevier
Cultured endothelial cells from bovine thoracic aortas conditioned with serum-free culture
media released an endothelin-1 (ET)-1-like substance. Concentrations of ET-1-like material …
media released an endothelin-1 (ET)-1-like substance. Concentrations of ET-1-like material …
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