Effects of allergen immunotherapy on follicular regulatory T... : Current Opinion in Allergy and
Clinical Immunology Effects of allergen immunotherapy on follicular regulatory T cells : Current …

Background The function of follicular regulatory T (T FR) cells, especially in regulating IgE
production in patients with allergic diseases, is poorly understood. Objective We sought to …

Summary Allergen-specific IL-4+ Tfh cells contribute to the production of allergen-specific
IgE and correlate with clinical efficacy of AIT in allergic rhinitis patients, which suggest …

A major pathway for the development of allergic disease is the production of IgE antibodies
specific for allergenic antigens. Once IgE is bound to mast cells and basophils via the high …

Highlights•IgE production in allergies is primarily driven by the T follicular helper (Tfh) cells,
rather than by Th2 cells.•Recent studies highlight the heterogeneity in Tfh cell populations …

Allergic diseases are characterized by overactive type 2 immune responses to allergens and
immunoglobulin E (IgE)‐mediated hypersensitivity. Emerging evidence suggests that …

Antibody responses are critical for protection against pathogens. However, diseases such as
allergic rhinitis or food allergy result from aberrant production of IgE antibodies against …

Background TH 2 cells have long been believed to play a pivotal role in allergic immune
responses, including IgE antibody production and type 2 cytokine–mediated inflammation …

The prevalence of allergies such as allergic conjunctivitis, allergic rhinitis, rhinosinusitis,
bronchial asthma, and food allergies has been increasing in recent years, and allergic …

LETTERS TO THE EDITOR 775 frequently coexpressed on a single-cell level, whereas
Granzyme A is expressed by a different subpopulation within the CXCR5lo cells. Given the …