Cerebral amyloid angiopathy is associated with executive dysfunction and mild cognitive impairment
NF Case, A Charlton, A Zwiers, S Batool, CR McCreary… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Autopsy studies suggest that cerebral amyloid angiopathy (CAA)
is associated with cognitive impairment and risk for dementia. We analyzed …
is associated with cognitive impairment and risk for dementia. We analyzed …
In pre-clinical AD small vessel disease is associated with altered hippocampal connectivity and atrophy
ABSTRACT Objective Small Vessel Disease (SVD) is known to be associated with higher
AD risk, but its relationship to amyloidosis in the progression of AD is unclear. In this cross …
AD risk, but its relationship to amyloidosis in the progression of AD is unclear. In this cross …
MRI markers of small vessel disease and the APOE allele in cognitive impairment
Objective The apolipoprotein E (APOE) ε4 allele is the main genetic risk factor for dementia
and Alzheimer's disease (AD), but the underlying mechanism for the increased risk is not …
and Alzheimer's disease (AD), but the underlying mechanism for the increased risk is not …
Comorbid amyloid‐β pathology affects clinical and imaging features in VCD
JF Leijenaar, C Groot, CH Sudre… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction To date, the clinical relevance of comorbid amyloid‐β (Aβ) pathology in patients
with vascular cognitive disorders (VCD) is largely unknown. Methods We included 218 VCD …
with vascular cognitive disorders (VCD) is largely unknown. Methods We included 218 VCD …
Brain amyloid β, cerebral small vessel disease, and cognition: a memory clinic study
FN Saridin, S Hilal, SG Villaraza, A Reilhac… - Neurology, 2020 - AAN Enterprises
Objective To evaluate the association between brain amyloid β (Aβ) and cerebral small
vessel disease (CSVD) markers, as well as their joint effect on cognition, in a memory clinic …
vessel disease (CSVD) markers, as well as their joint effect on cognition, in a memory clinic …
Association between white matter hyperintensity and medial temporal atrophy at various stages of Alzheimer's disease
Background and purpose Whilst there is evidence implicating small vessel cerebrovascular
disease in the pathogenesis of Alzheimer's disease (AD), its specific contribution to the …
disease in the pathogenesis of Alzheimer's disease (AD), its specific contribution to the …
Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly
P Vemuri, TG Lesnick, SA Przybelski, DS Knopman… - Brain, 2015 - academic.oup.com
Our primary objective was to investigate a biomarker driven model for the interrelationships
between vascular disease pathology, amyloid pathology, and longitudinal cognitive decline …
between vascular disease pathology, amyloid pathology, and longitudinal cognitive decline …
White matter atrophy in cerebral amyloid angiopathy
P Fotiadis, YD Reijmer, SJ Van Veluw… - Neurology, 2020 - AAN Enterprises
Objective We postulated that cerebral amyloid angiopathy (CAA) is associated with white
matter atrophy (WMA) and that WMA can be related to cognitive changes in CAA. Methods …
matter atrophy (WMA) and that WMA can be related to cognitive changes in CAA. Methods …
The temporal relationships between white matter hyperintensities, neurodegeneration, amyloid beta, and cognition
Abstract Introduction Cognitive decline in Alzheimer's disease is associated with amyloid
beta (Aβ) accumulation, neurodegeneration, and cerebral small vessel disease, but the …
beta (Aβ) accumulation, neurodegeneration, and cerebral small vessel disease, but the …
Exploring the effects of coexisting amyloid in subcortical vascular cognitive impairment
Abstract Background Mixed pathology, particularly Alzheimer's disease with cerebrovascular
lesions, is reported as the second most common cause of dementia. Research on mixed …
lesions, is reported as the second most common cause of dementia. Research on mixed …