Introduction: Cerebral small-vessel disease (SVD) represents the most frequent type of
vascular brain lesions, often coexisting with Alzheimer disease (AD). By quantifying white …

Purpose We investigated the frequency and clinical significance of amyloid β (Aβ) positivity
on PET in patients with cerebral amyloid angiopathy (CAA). Methods We recruited 65 …

Background: Cerebral amyloid angiopathy (CAA) is associated with cognitive decline. CAA
has diverse impacts on brain structure and function; however, the brain lesions that mediate …

Background The underlying cause of cognitive decline in individuals who are positive for
biomarkers of neurodegeneration (N) but negative for biomarkers of amyloid‐beta (A) …

Background and Purpose—Cerebral small vessel disease (SVD) is a frequent pathology in
aging and contributor to the development of dementia. Plasma Aβ (amyloid β) levels may be …

Background Growing evidence suggests that not only cerebrovascular disease but also
Alzheimer's disease (AD) pathological process itself cause cerebral white matter …

Background and Objectives Reduced cerebrovascular reactivity is proposed to be a feature
of cerebral amyloid angiopathy (CAA) but has not been measured directly. Employing a …

Abstract Background/Objectives To examine the association between white matter
hyperintensities (WMH) and cognitive domains such as memory and executive function (EF) …

The importance of early interventions in Alzheimer's disease (AD) emphasizes the need to
accurately and efficiently identify at-risk individuals. Although many dementia prediction …

Objective Recent studies suggest that white matter hyperintensities (WMH) on MRI, which
primarily reflect small vessel cerebrovascular disease, may play a role in the evolution of …