The Role of Exercise in Maintaining Mitochondrial Proteostasis in Parkinson's Disease

J Li, Y Xu, T Liu, Y Xu, X Zhao, J Wei - International Journal of Molecular …, 2023 - mdpi.com
Parkinson's disease (PD) is the second most common rapidly progressive
neurodegenerative disease and has serious health and socio-economic consequences …

Mitochondrial dysfunction and Parkinson's disease: pathogenesis and therapeutic strategies

S Moradi Vastegani, A Nasrolahi, S Ghaderi… - Neurochemical …, 2023 - Springer
Parkinson's disease (PD) is a common age-related neurodegenerative disorder whose
pathogenesis is not completely understood. Mitochondrial dysfunction and increased …

Involvement of mitochondria in Parkinson's disease

CJ Choong, H Mochizuki - International Journal of Molecular Sciences, 2023 - mdpi.com
Mitochondrial dysregulation, such as mitochondrial complex I deficiency, increased
oxidative stress, perturbation of mitochondrial dynamics and mitophagy, has long been …

Dietary macronutrient management to treat mitochondrial dysfunction in Parkinson's disease

R Bajracharya, NA Youngson, JWO Ballard - International journal of …, 2019 - mdpi.com
Mitochondrial dysfunction has been demonstrated to play an important role in the
pathogenesis of Parkinson's disease (PD). The products of several PD-associated genes …

[HTML][HTML] Mitochondrial homeostasis regulation: A promising therapeutic target for Parkinson's disease

MF Yao, T Dang, HJ Wang, XZ Zhu, C Qiao - Behavioural Brain Research, 2023 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease characterized by progressive loss
of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) and the …

Exercise-boosted mitochondrial remodeling in Parkinson's disease

JC Magaña, CM Deus, M Giné-Garriga, J Montané… - Biomedicines, 2022 - mdpi.com
Parkinson's disease (PD) is a movement disorder characterized by the progressive
degeneration of dopaminergic neurons resulting in dopamine deficiency in the striatum …

Ameliorating Mitochondrial Dysfunction for the Therapy of Parkinson's Disease

Q Zheng, H Liu, Y Gao, G Cao, Y Wang, Z Li - Small, 2024 - Wiley Online Library
Parkinson's disease (PD) is currently the second most incurable central neurodegenerative
disease resulting from various pathogenesis. As the “energy factory” of cells, mitochondria …

Emerging concepts of mitochondrial dysfunction in Parkinson's disease progression: Pathogenic and therapeutic implications

L Rani, AC Mondal - Mitochondrion, 2020 - Elsevier
Mitochondria are very dynamic organelle which plays a multifactorial role for a broad range
of physiological processes inside the cell to maintain neural circuit integrity. They are …

A systematic review of molecular approaches that link mitochondrial dysfunction and neuroinflammation in Parkinson's disease

S Mani, M Sevanan, A Krishnamoorthy, S Sekar - Neurological Sciences, 2021 - Springer
Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder that
affects 1% of the population worldwide. Etiology of PD is likely to be multi-factorial such as …

Mitochondrial dysfunction and oxidative stress in Parkinson's disease

SR Subramaniam, MF Chesselet - Progress in neurobiology, 2013 - Elsevier
Parkinson's disease (PD) is a movement disorder that is characterized by the progressive
degeneration of dopaminergic neurons in substantia nigra pars compacta resulting in …