Cortical expansion and folding are key processes in human brain development and
evolution and are considered to be principal elements of intellectual ability. How cortical …

During cortical development, human basal radial glial cells (bRGCs) are highly capable of
sustained self-renewal and neurogenesis. Selective pressures on this cell type may have …

FOXP1 is a member of FOXP subfamily transcription factors. Mutations in FOXP1 gene have
been found in various development-related cognitive disorders. However, little is known …

The cortex consists of 100s of neuronal subtypes that are organized into distinct functional
regions; however, the mechanisms underlying cell fate determination remain unclear. Foxg1 …

FOXG1 is a critical transcription factor in human brain where loss-of-function mutations
cause a severe neurodevelopmental disorder, while increased FOXG1 expression is …

The transcription factor FoxP2 has been associated with the development of human speech
but the underlying cellular function of FoxP2 is still unclear. Here we provide evidence that …

Mutations of the transcription factor FOXP2 in humans cause a severe speech and language
disorder. Disruption of Foxp2 in songbirds or mice also leads to deficits in song learning or …

Strategies to enhance hippocampal precursor cells efficiently differentiate into neurons
could be crucial for structural repair after neurodegenerative damage. FOXG1 has been …

Foxg1 is a transcription factor critical for the development of the mammalian telencephalon.
Foxg1 controls the proliferation of dorsal telencephalon progenitors and the specification of …

In vertebrate embryogenesis, neural induction is the earliest step through which the fate of
embryonic ectoderm to neuroectoderm becomes determined. Cells in the neuroectoderm or …