First results with Lu-177-PSMA617 in targeted radionuclide therapy of patients with metastatic hormone-refractory prostate cancer.

C Kratochwil, F Giesel, M Benesova, A Afshar-Oromieh… - 2015 - Soc Nuclear Med
390 Objectives We report our clinical experience with PSMA targeted radionuclide therapy
of patients with metastatic hormone-refractory prostate cancer in regard to toxicity and …

An intrapatient dosimetry comparison of 177Lu-rhPSMA-10.1 and 177Lu-PSMA-I&T in patients with metastatic castration-resistant prostate cancer

A Rinscheid, A Gäble, G Wienand, C Pfob… - Journal of Nuclear …, 2023 - Soc Nuclear Med
As the use of radioligand therapy moves earlier in the prostate cancer timeline, minimizing
the absorbed dose to normal organs while maintaining high tumor radiation doses becomes …

Why Targeting of PSMA Is a Valuable Addition to the Management of Castration-Resistant Prostate Cancer: The Urologist's Point of View

BA Hadaschik, M Boegemann - Journal of Nuclear Medicine, 2017 - Soc Nuclear Med
Prostate cancer (PC) is the most common cancer and the third most common cause of
cancer-related deaths in men in developed countries (1). In general, PC starts out as an …

[HTML][HTML] Kidney absorbed radiation doses for [177Lu] Lu-PSMA-617 and [177Lu] Lu-PSMA-I&T determined by 3D clinical dosimetry

MJM Uijen, BM Privé, CML Van Herpen… - Nuclear Medicine …, 2023 - journals.lww.com
Purpose For prostate-specific membrane antigen-directed radioligand therapy (PSMA-
RLT),[177 Lu] Lu-PSMA-617 and [177 Lu] Lu-PSMA-I&T are the currently preferred …

The VISION forward: recognition and implication of PSMA−/18F-FDG+ mCRPC

H Jadvar - Journal of Nuclear Medicine, 2022 - Soc Nuclear Med
Metastatic castration resistant prostate cancer (mCRPC) is incurable. The expression of the
transmembrane protein prostate-specific membrane antigen (PSMA) is markedly increased …

[HTML][HTML] Analysis of PSMA expression and outcome in patients with advanced prostate cancer receiving 177Lu-PSMA-617 radioligand therapy

R Seifert, K Seitzer, K Herrmann, K Kessel… - Theranostics, 2020 - ncbi.nlm.nih.gov
Abstract Rationale: PSMA-PET-CT enables measuring molecular expression of prostate-
specific membrane antigen (PSMA) in vivo, which is the target molecule of 177 Lu-PSMA …

Liver enzyme elevation after 177Lu-PSMA radioligand therapy for metastasized castration-resistant prostate cancer

H Treiber, A König, A Neesse, A Richter… - Journal of Nuclear …, 2021 - Soc Nuclear Med
177Lu-PSMA radioligand therapy is a promising new option for patients with metastasized
castration-resistant prostate cancer, and the spectrum of adverse events with this treatment …

Rapid tumor washout of 177Lu-PSMA radioligand in renal cell carcinoma

J Zhang, C Schuchardt, X Chen… - Clinical Nuclear …, 2023 - journals.lww.com
The role of prostate-specific membrane antigen (PSMA) targeted molecular imaging and
radionuclide therapy in prostate cancer is well known. PSMA is also overexpressed in the …

Hematotoxicity after radioligand therapy of metastatic castrate-resistant prostate cancer with 177Lu-PSMA-617

S Zimbelmann, E Eppard, S Hauser, S Kuerpig… - 2016 - Soc Nuclear Med
1429 Objectives Radioligand therapy (RLT) with 177Lu-PSMA-617 (Lu-PSMA)(prostate-
specific membrane antigen) is a novel targeted therapy for metastatic prostate cancer. There …

Systemic radioligand therapy with 177Lu-PSMA I&T in patients with metastatic castration-resistant prostate cancer

M Eiber, M Heck, R Tauber, I Rauscher, DA Calogero… - 2016 - Soc Nuclear Med
61 Objectives Prostate-specific membrane antigen (PSMA) is a potential therapeutic target
in patients with metastatic castration-resistant prostate cancer (mCRPC). To report our initial …