Global metabolic profiling of baculovirus infection in silkworm hemolymph shows the importance of amino-acid metabolism

M Feng, S Fei, J Xia, M Zhang, H Wu, L Swevers, J Sun - Viruses, 2021 - mdpi.com
Viruses rely on host cell metabolism to provide the necessary energy and biosynthetic
precursors for successful viral replication. Infection of the silkworm, Bombyx mori, by Bombyx …

Identification of key metabolic pathways reprogrammed by BmNPV in silkworm Bombyx mori

W Zhou, D Song, H Chen, Q Tang, Q Yu, S Huo… - Journal of Invertebrate …, 2022 - Elsevier
Elucidating the mechanism of infection of Bombyx mori nuclear polyhedrosis virus (BmNPV)
and host antiviral response remains a major scientific task in sericulture. Virus invasion …

Response to Bombyx mori nucleopolyhedrovirus infection in silkworm: Gut metabolites and microbiota

X Shi, Y Zhang, T Zhu, N Li, S Sun, M Zhu, J Pan… - Developmental & …, 2021 - Elsevier
The diversity of microbiota and metabolites in the digestive tract gut is important in
physiology and homeostasis, nutrient uptake and virus infection. In lepidopteran insect …

Metabolic characterization of hemolymph in Bombyx mori varieties after Bombyx mori nucleopolyhedrovirus infection by GC-MS-based metabolite profiling

H Qian, H Guo, X Zhang, M Liu, G Zhao, A Xu, G Li - Archives of Virology, 2022 - Springer
Abstract The" Huakang 2" silkworm variety, bred by the Sericulture Research Institute of the
Chinese Academy of Agricultural Sciences, is highly resistant to Bombyx mori …

Metabolic Characterisation of the Midgut of Bombyx mori Varieties after BmNPV Infection Using GC-MS-Based Metabolite Profiling

H Qian, G Li, G Zhao, M Liu, A Xu - International Journal of Molecular …, 2020 - mdpi.com
Bombyx mori nucleopolyhedrovirus (BmNPV) is a silkworm disease that is especially
harmful to cocoon production and seriously restricts sericultural development. Our laboratory …

The Antiviral Molecule 5-Pyridoxolactone Identified Post BmNPV Infection of the Silkworm, Bombyx mori

X Hua, Q Zhang, W Xu, X Wang, F Wang… - International Journal of …, 2021 - mdpi.com
Bombyx mori nucleopolyhedrovirus (BmNPV) is a pathogen that causes great economic
losses in sericulture. Many genes play a role in viral infection of silkworms, but silkworm …

A 1H NMR based study of hemolymph metabonomics in different resistant silkworms, Bombyx mori (Lepidotera), after BmNPV inoculation

X Wang, Z Shao, Y Zhang, TT Vu, Y Wu, J Xu… - Journal of insect …, 2019 - Elsevier
Bombyx mori nucleopolyhedrovirus (BmNPV) is a primary silkworm pathogen, and the
molecular mechanism of silkworm defense to BmNPV infection is still unclear. Herein …

Proteomics analysis of digestive juice from silkworm during Bombyx mori nucleopolyhedrovirus infection

X Hu, M Zhu, S Wang, L Zhu, R Xue, G Cao… - …, 2015 - Wiley Online Library
Previous studies have analyzed the midgut transcriptome and proteome after challenge with
Bombyx mori nucleopolyhedrovirus (BmNPV), however little information is available on the …

Unraveling the innate immune responses of Bombyx mori hemolymph, fat body, and midgut to Bombyx mori nucleopolyhedrovirus oral infection by metabolomic …

G Wang, D Xu, D Guo, Y Zhang, X Mai… - Archives of Insect …, 2021 - Wiley Online Library
Bombyx mori nucleopolyhedrovirus (BmNPV) infection causes a series of physiological and
pathological changes in Bombyx mori (B. mori). Here, a metabolomic study of the innate …

A Metabolomics Approach to Unravel Cricket Paralysis Virus Infection in Silkworm Bm5 Cells

LL Wang, L Swevers, C Rombouts, I Meeus… - Viruses, 2019 - mdpi.com
How a host metabolism responds to infection with insect viruses and how it relates to
pathogenesis, is little investigated. Our previous study observed that Cricket paralysis virus …