Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty acyl-CoAs, but their
biological functions remain incompletely understood. Thioesterase superfamily member 2 …

Mammalian acyl-CoA thioesterases (Acots) catalyze the hydrolysis of fatty acyl-CoAs to form
free fatty acids plus CoA, but their metabolic functions remain undefined. Thioesterase …

Objective Non-shivering thermogenesis in brown adipose tissue (BAT) plays a central role in
energy homeostasis. Thioesterase superfamily member 1 (Them1), a BAT-enriched long …

Members of the acyl-CoA thioesterase (Acot) gene family catalyze the hydrolysis of fatty acyl-
CoA thioesters. Thioesterase superfamily member (Them) 1 (synonym: Acot11) is enriched …

Members of the acyl-CoA thioesterase (Acot) gene family catalyze the hydrolysis of fatty acyl-
CoAs, but their biological functions remain unknown. Thioesterase superfamily member 2 …

Nonshivering thermogenesis occurs in brown adipose tissue to generate heat in response to
cold ambient temperatures. Thioesterase superfamily member 1 (Them1) is transcriptionally …

Background and Aims Obesity‐induced pathogenesis of nonalcoholic fatty liver disease
(NAFLD) and nonalcoholic steatohepatitis (NASH) is associated with increased de novo …

Thioesterase superfamily member 1 (Them1; synonyms acyl-CoA thioesterase 11 and
StarD14) is highly expressed in brown adipose tissue and limits energy expenditure in mice …

Them2 (thioesterase superfamily member 2) is a 140-amino-acid protein of unknown
biological function that comprises a single hotdog fold thioesterase domain. On the basis of …

Thioesterase superfamily member 1 (Them1) is an acyl-CoA thioesterase that is highly
expressed in brown adipose tissue, where it functions to suppress energy expenditure …