Trace metals such as iron and zinc are vital nutrients known to play key roles in prokaryotic
processes including gene regulation, catalysis, and protein structure. Metal sequestration by …

Neisseria gonorrhoeae employs high-affinity metal acquisition systems to obtain necessary
nutrients, such as iron (Fe) and zinc (Zn) from the environment. Because growth and …

Transition metals are essential for metalloprotein function among all domains of life.
Humans utilize nutritional immunity to limit bacterial infections, employing metalloproteins …

Neisseria gonorrhoeae and Neisseria meningitidis are human-specific pathogens in the
Neisseriaceae family that can cause devastating diseases. Although both species inhabit …

The bacterium Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhea.
N. gonorrhoeae is an obligate human pathogen that colonizes mucosal surfaces of the …

Biological-relevant transition metals such as iron, zinc, manganese, and copper are at the
center of a battle between pathogens and hosts, playing a major role in the outcome of …

Transition metals are essential nutrients for all organisms and important players in the host–
microbe interaction. During bacterial infection, a tug-of-war between the host and microbe …

To ensure survival, most bacteria must acquire iron, a resource that is sequestered by
mammalian hosts. Pathogenic bacteria have therefore evolved intricate systems to sense …

Neisseria gonorrhoeae is a strict human pathogen that causes the sexually transmitted
infection termed gonorrhea. The gonococcus can survive extracellularly and intracellularly …

To ensure survival in the host, bacteria have evolved strategies to acquire the essential
element iron. In Neisseria gonorrhoeae, the ferric uptake regulator Fur regulates metabolism …