Dendritic cells (DCs) are the most potent professional antigen-presenting cells, capable of
initiating proper adaptive immune responses. Although tumor-infiltrating DCs are able to …

The characterization of tumorassociated antigens recognized by human T lymphocytes in a
major histocompatibility complex (MHC) restricted fashion has opened new possibilities for …

Advances in the understanding of the immunoregulatory functions of dendritic cells (DCs) in
animal models and humans have led to their exploitation as anticancer vaccines. Although …

Dendritic cells (DCs) play a central role in the initiation and regulation of primary immune
responses. DCs loaded with tumor-associated antigens induce anti-tumoral cytotoxic T cells …

Exploitation of the patient's own immune system to induce antitumor immune responses
using dendritic cell (DC) immunotherapy has been established in early clinical trials as a …

Dendritic cells (DCs) are the most powerful professional antigen-presenting cells and are
unique in their capability to initiate, maintain and regulate the intensity of primary immune …

The discovery that dendritic cells (DC) play a key role in regulating antitumor immunity has
prompted considerable efforts in developing DC-based cancer vaccines for use in clinical …

Dendritic cells (DC) are recognized as the most potent antigen-presenting cells with the
ability to stimulate naive resting T cells and to initiate primary immune responses …

Cancer immunotherapy seeks to mobilize a patient's immune system for therapeutic benefit.
It can be passive, that is, transfer of immune effector cells (T cells) or proteins (antibodies), or …

Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …